Protein Information

Name ATPase
Synonyms ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1…

Compound Information

Name thallium sulfate
CAS sulfuric acid dithallium(1+) salt

Reference List

PubMed Abstract RScore(About this table)
2131777 Careaga-Olivares J, Morales-Aguilera A: [Acute effects of the administration of potassium on the organ uptake of Tl+ in the rabbit]. Arch Invest Med. 1990 Jul-Sep;21(3):273-7.


The skeletal muscle seems to manage the thallium-potassium interaction depending on the activation of sodium-potassium ATPase.
2(0,0,0,2) Details
8818864 Appenroth D, Tiller S, Gambaryan S, Winnefeld K, Fleck C, Braunlich H: Ontogenetic aspects of thallium-induced nephrotoxicity in rats. J Appl Toxicol. 1996 May-Jun;16(3):235-43.


The activity of Na+/K (+)-ATPase in rat renal tissues was found to be involved in the mechanisms of Tl enrichment in renal tissue, being an indirect determinant of Tl nephrotoxicity.
1(0,0,0,1) Details
7900161 Appenroth D, Gambaryan S, Winnefeld K, Leiterer M, Fleck C, Braunlich H: Functional and morphological aspects of thallium-induced nephrotoxicity in rats. Toxicology. 1995 Feb 27;96(3):203-15.


Other parameters such as Tl concentration, changes in water content and the activity of Na+/K (+)-ATPase as well as the diuretic effect of furosemide confirmed the Tl effect to be localized in the renal medulla.
1(0,0,0,1) Details