Protein Information

Name P glycoprotein
Synonyms ABC20; MDR1; ABCB 1; ABCB1; ATP binding cassette sub family B member 1; CD243; CD243 antigen; CLCS…

Compound Information

Name prochloraz
CAS

Reference List

PubMed Abstract RScore(About this table)
11408081 Sturm A, Cravedi JP, Segner H: Prochloraz and nonylphenol diethoxylate inhibit an mdr1-like activity in vitro, but do not alter hepatic levels of P-glycoprotein in trout exposed in vivo. Aquat Toxicol. 2001 Aug;53(3-4):215-28.

The inhibition by prochloraz and NP2EO of the md r1-like mechanism in trout hepatocytes suggests that water pollutants can interfere with P-gp-function in fish and thus may impair the organismal defense against xenobiotics.
116(1,2,2,6) Details