Protein Information

Name aldolase A
Synonyms ALDA; ALDOA; ALDOA protein; Aldolase 1; Aldolase A; Fructoaldolase A; Fructose bisphosphate aldolase; Fructose bisphosphate aldolase A…

Compound Information

Name azobenzene
CAS diphenyldiazene

Reference List

PubMed Abstract RScore(About this table)
3093278 Lamas E, Schweighoffer F, Kahn A: Early modifications of gene expression induced in liver by azo-dye diet. FEBS Lett. 1986 Oct 6;206(2):229-32.

The expression and regulation of the phosphoenolpyruvate carboxykinase gene were not grossly modified by feeding rats a 3'-methyl-4-(dimethylamino) azobenzene-containing diet despite maximum expression of the L-type pyruvate kinase gene being dramatically reduced as early as the 24th hour of the carcinogenic diet.
The amount of aldolase A mRNA fell quickly after termination of carcinogen administration, levels being normal at the 2nd-3rd day.
1(0,0,0,1) Details
2410270 Lamas E, Schweighoffer F, Van Els C, Bachner L, Marie J, Kahn A: Modifications of the expression of liver-specific and non-specific messenger RNAs during azo-dye hepatocarcinogenesis. Eur J Biochem. 1985 Jul 15;150(2):395-9.

The expression of specific and non-specific rat liver messenger RNAs has been studied during 3'-methyl-4-(dimethylamino) azobenzene (3'-MeDAB) carcinogenesis, using cDNA probes complementary to mRNAs encoding aldolase A and B, L-type pyruvate kinase, albumin, alpha-fetoprotein, transferrin and an unidentified 2.7 X 10 (3)-base mRNA. mRNAs specific for undifferentiated cells, such as those encoding aldolase A and the unidentified 2.7 X 10 (3)-base species were re-expressed very early, being easily detectable at the 1st week of 3'-MeDAB treatment.
31(0,1,1,1) Details