| Name | glutamate receptor |
|---|---|
| Synonyms | GRINL1A; GUP1; GUP2; GRINL1A combined protein; GRINL1A combined protein Gcom10; GRINL1A combined protein Gcom10 precursor; GRINL1A combined protein Gcom11; GRINL1A combined protein Gcom11 precursor… |
| Name | azobenzene |
|---|---|
| CAS | diphenyldiazene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19342491 | Numano R, Szobota S, Lau AY, Gorostiza P, Volgraf M, Roux B, Trauner D, Isacoff EY: Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6814-9. Epub 2009 Apr 2. We have studied the geometric and conformational factors that determine the efficacy of PTL gating in the ionotropic glutamate receptor iGluR6 using a family of photoiosomerizable MAG (maleimide-azobenzene- PTLs that covalently attach to the clamshell ligand-binding domain. |
31(0,1,1,1) | Details |
| 16408092 | Volgraf M, Gorostiza P, Numano R, Kramer RH, Isacoff EY, Trauner D: Allosteric control of an ionotropic glutamate receptor with an optical switch. Nat Chem Biol. 2006 Jan;2(1):47-52. Epub 2005 Dec 11. An agonist is covalently tethered to the protein through an azobenzene moiety, which functions as the optical switch. |
2(0,0,0,2) | Details |
| 17578923 | Gorostiza P, Volgraf M, Numano R, Szobota S, Trauner D, Isacoff EY: Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):10865-70. Epub 2007 Jun 19. We have synthesized photoswitches that covalently modify target proteins and reversibly present and withdraw a ligand from its binding site due to photoisomerization of an azobenzene linker. |
1(0,0,0,1) | Details |