| Name | demethylase |
|---|---|
| Synonyms | DMTase; Demethylase; MBD 2; MBD2; Methyl CpG binding domain protein 2; Methyl CpG binding protein MBD2; NY CO 41; Demethylases… |
| Name | propiconazole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3190755 | Leslie C, Reidy GF, Stacey NH: The effects of propiconazole on hepatic xenobiotic biotransformation in the rat. Biochem Pharmacol. 1988 Nov 1;37(21):4177-81. Induction was seen for cytochrome P-450, ethoxyresorufin-O-deethylase, ethoxycoumarin-O-deethylase, aldrin epoxidase, aminopyrine N-demethylase and microsomal expoxide hydrolase activities. |
2(0,0,0,2) | Details |
| 18024679 | Luo CX, Schnabel G: The cytochrome P450 14alpha-demethylase gene is a demethylation inhibitor fungicide resistance determinant in Monilinia fructicola field isolates from Georgia. Appl Environ Microbiol. 2008 Jan;74(2):359-66. Epub 2007 Nov 16. Gene expression was not induced in mycelium of DMI-R or DMI-S isolates treated with 0.3 mug of propiconazole/ml. |
2(0,0,0,2) | Details |
| 15916909 | Wyand RA, Brown JK: Sequence variation in the CYP51 gene of Blumeria graminis associated with resistance to sterol demethylase inhibiting fungicides. Fungal Genet Biol. 2005 Aug;42(8):726-35. |
2(0,0,0,2) | Details |
| 19418481 | Canas-Gutierrez GP, Angarita-Velasquez MJ, Restrepo-Florez JM, Rodriguez P, Moreno CX, Arango R: Analysis of the CYP51 gene and encoded protein in propiconazole-resistant isolates of Mycosphaerella fijiensis. Pest Manag Sci. 2009 Aug;65(8):892-9. CONCLUSION: Several changes in the sequence of the gene encoding sterol 14alpha-demethylase were found that have been described in other fungi as being correlated with resistance to azole fungicides. |
1(0,0,0,1) | Details |
| 7986207 | Ronis MJ, Ingelman-Sundberg M, Badger TM: Induction, suppression and inhibition of multiple hepatic cytochrome P450 isozymes in the male rat and bobwhite quail (Colinus virginianus) by biosynthesis inhibiting fungicides (EBIFs). Biochem Pharmacol. 1994 Nov 16;48(10):1953-65. In the current study, we examined the effects of two EBIFs in clinical use, and ketoconazole, and two agricultural EBIFs, propiconazole and vinclozolin, on hepatic monooxygenase activities and P450 apoprotein expression in the male Sprague-Dawley rat and the male bobwhite quail. EBIFs produced Type II binding spectra with hepatic microsomes from both species and were effective inhibitors of methoxyresorufin O-demethylase, an activity selective for P450 isozymes in gene family 1. |
1(0,0,0,1) | Details |