Protein Information

Name aldehyde oxidase
Synonyms AO; AOH 1; AOH1; AOX 1; AOX1; Aldehyde Oxidase; Aldehyde oxidase 1; Aldeyde oxidase…

Compound Information

Name diphenyl sulfone
CAS 1,1′-sulfonylbisbenzene

Reference List

PubMed Abstract RScore(About this table)
4051501 Yoshihara S, Tatsumi K: Guinea pig liver aldehyde oxidase as a sulfoxide reductase: its purification and characterization. Arch Biochem Biophys. 1985 Oct;242(1):213-24.

This enzyme also reduced dibenzyl sulfoxide, phenothiazine sulfoxide, D-biotin methyl ester d-sulfoxide, and quinoline N-oxide, but not L-methionine sulfoxide, dimethyl sulfoxide, D-biotin methyl ester l-sulfoxide, and D-biotin d- and l-sulfoxides, as well as diphenyl sulfone.
5(0,0,0,5) Details
1981531 Yoshihara S, Tatsumi K: Metabolism of diphenyl sulfoxide in perfused guinea pig liver. Drug Metab Dispos. 1990 Nov-Dec;18(6):876-81.

Involvement of aldehyde oxidase as a sulfoxide reductase..
DPSO was exclusively converted into diphenyl sulfone (DPSO2), an oxidative metabolite, under normoxia.
2(0,0,0,2) Details