| Name | cholinesterases |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | mevinphos |
|---|---|
| CAS | methyl 3-[(dimethoxyphosphinyl)oxy]-2-butenoate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18966276 | Kumaran S, Morita M: Application of a cholinesterase biosensor to screen for organophosphorus pesticides extracted from soil. Talanta. 1995 Apr;42(4):649-55. Based on the principle of enzyme inactivation, a butyrylcholinesterase (EC 3.1.1.8.) biosensor, to determine some organophosphorus (ORP) pesticides (Fenitrothion, Diazinon, Parathion ethyl, Mevinphos and Heptenophos) in soil extracts, is presented. |
32(0,1,1,2) | Details |
| 4644700 | Watanabe PG, Sharma RP: Inhibition of subcellular cholinesterases by 2-carbomethoxy-l-methylvinyl dimethyl (mevinphos) in vitro and in vivo. Toxicol Appl Pharmacol. 1972 Dec;23(4):692-700. |
31(0,1,1,1) | Details |
| 595013 | Verberk MM: Incipient cholinesterase inhibition in volunteers ingesting monocrotophos or mevinphos for one month. Toxicol Appl Pharmacol. 1977 Nov;42(2):345-50. |
81(1,1,1,1) | Details |
| 2729280 | Ames RG, Brown SK, Mengle DC, Kahn E, Stratton JW, Jackson RJ: Cholinesterase activity depression among California agricultural pesticide applicators. Am J Ind Med. 1989;15(2):143-50. Pesticides most frequently associated with cholinesterase depressions exceeding California threshold values included mevinphos (Phosdrin), oxydemeton methyl (Metasystox-R), methomyl (Lannate), and acephate (Orthene); these pesticides included organophosphates in toxicity categories I and II and one in toxicity category I. |
9(0,0,1,4) | Details |
| 4013266 | Midtling JE, Barnett PG, Coye MJ, Velasco AR, Romero P, Clements CL, O'Malley MA, Tobin MW, Rose TG, Monosson IH: Clinical management of field worker organophosphate poisoning. West J Med. 1985 Apr;142(4):514-8. A group of 16 cauliflower workers poisoned by residues of the organophosphate insecticides mevinphos and phosphamidon was followed in weekly clinics with interviews and determinations of plasma and erythrocyte cholinesterase levels. |
8(0,0,1,3) | Details |
| 3827420 | Coye MJ, Barnett PG, Midtling JE, Velasco AR, Romero P, Clements CL, Rose TG: Clinical confirmation of organophosphate poisoning by serial cholinesterase analyses. Arch Intern Med. 1987 Mar;147(3):438-42. |
5(0,0,0,5) | Details |
| 7097797 | Skinner CS, Kilgore WW: Application of a dermal self-exposure model to worker reentry. J Toxicol Environ Health. 1982 Mar;9(3):461-81. Blood cholinesterases were monitored on d -3 and -1 before exposure and for 4--6 d during exposure to foliar residues. Azinphos-methyl and mevinphos produced no significant responses in muzzled mice at maximal foliar concentrations. |
5(0,0,0,5) | Details |
| 6737998 | Durand P, Nicaud JM, Mallevialle J: Detection of organophosphorous pesticides with an immobilized cholinesterase electrode. J Anal Toxicol. 1984 May-Jun;8(3):112-7. Technical grade compounds of methylparathion, azinphosethyl , and mevinphos were used as examples, and detected from ppm to several ppb after oxidative treatment. |
4(0,0,0,4) | Details |
| 3788984 | Coye MJ, Barnett PG, Midtling JE, Velasco AR, Romero P, Clements CL, O'Malley MA, Tobin MW, Lowry L: Clinical confirmation of organophosphate poisoning of agricultural workers. Am J Ind Med. 1986;10(4):399-409. A group of 31 lettuce harvesters exposed to the organophosphate pesticide mevinphos presented to a local emergency room with moderate cholinergic symptoms and eye and skin irritation, with 22 of the subjects (76%) reporting three or more symptoms. None had baseline cholinesterase values, and plasma cholinesterase activity for all but two workers was above the lower limit of the laboratory normal range. |
3(0,0,0,3) | Details |
| 8620316 | Kassa J, Bajgar J: [Comparison of the therapeutic effectiveness of selected cholinesterase reactivators with atropine in acute fosdrine poisoning in mice]. Ceska Slov Farm. 1996 Feb;45(1):31-4. |
2(0,0,0,2) | Details |
| 9441373 | Kassa J: [Comparison of the effect of selected cholinesterase reactivators combined with atropine on soman and fosdrin toxicity in mice]. Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl. 1995;38(1):63-6. |
2(0,0,0,2) | Details |
| 6138014 | Michalek H, Nemesio R, Meneguz A, Bisso GM: Interactions between anticholinesterase agents and neuroleptics in terms of cholinesterase inhibition in brain and other tissues of rats. Arch Toxicol Suppl. 1983;6:386-90. CPZ was found to potentiate slightly the effects of Mevinphos but did not interact with Carbaryl, Diazinon or Azinphos. |
1(0,0,0,1) | Details |
| 7387189 | Knaak JB, Jackson T, Fredrickson AS, Maddy KT, Akesson NB: Safety effectiveness of pesticide mixing-loading and application equipment used in 1976. Arch Environ Contam Toxicol. 1980;9(2):217-29. The effectiveness of currently used pesticide mixing-loading and application equipment in preventing workers from being exposed to cholinesterase (ChE) inhibiting pesticides was measured. |
1(0,0,0,1) | Details |
| 15179137 | Yen DH, Chan JY, Tseng HP, Huang CI, Lee CH, Chan SH, Chang AY: Depression of mitochondrial respiratory enzyme activity in rostral ventrolateral medulla during acute mevinphos intoxication in the rat. Shock. 2004 Apr;21(4):358-63. We conclude that Mev adversely effects cardiovascular control by acting as a cholinesterase inhibitor in the RVLM, whose neuronal activity is intimately related to the death process. |
1(0,0,0,1) | Details |
| 8349949 | Casale GP, Vennerstrom JL, Bavari S, Wang TL: Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected and organophosphate insecticides and congeners of carbaryl. Immunopharmacol Immunotoxicol. 1993 Mar-Jun;15(2-3):199-215. The anticholinesterase (antiCHE) insecticides, a large family of pesticides used extensively throughout the world, inhibit serine hydrolases by carbamylating or phosphorylating a serine residue at the catalytic site. The order of potency for T cell inhibition was carbaryl = dichlorvos > methiocarb > carbofuran > paraoxon > mevinphos > aldicarb = monocrotophos. |
1(0,0,0,1) | Details |
| 11702011 | Chang AY, Chan JY, Kao FJ, Huang CM, Chan SH: Engagement of inducible synthase at the rostral ventrolateral medulla during mevinphos intoxication in the rat. J Biomed Sci. 2001 Nov-Dec;8(6):475-83. We conclude that, as a cholinesterase inhibitor, Mev may induce toxicity via produced by iNOS on activation of the R by the accumulated in the RVLM. |
1(0,0,0,1) | Details |
| 7387190 | Knaak JB, Jackson T, Fredrickson AS, Rivera L, Maddy KT, Akesson NB: Safety effectiveness of closed-transfer, mixing-loading, and application equipment in preventing exposure to pesticides. Arch Environ Contam Toxicol. 1980;9(2):231-45. Mevinphos residues on cloth patches averaged 0.2 microgram/cm2. Blood cholinesterase (CHE) activities and urinary dialkyl levels of five mixer-loaders and four mixer-loader applicators, using a closed-transfer system in conjunction with mixing-loading and application equipment, were monitored over a period of 18 weeks. |
1(0,0,0,1) | Details |
| 11198355 | Yen DH, Yen JC, Len WB, Wang LM, Lee CH, Chan SH: Spectral changes in systemic arterial pressure signals during acute mevinphos intoxication in the rat. Shock. 2001 Jan;15(1):35-41. We conclude that the progressive accumulation of over time induced by a direct inhibition of Mev on cholinesterase in the NRVL may be responsible for the phasic changes in cardiovascular events over the course of acute Mev intoxication. |
1(0,0,0,1) | Details |
| 10022307 | Ray DE: Chronic effects of low level exposure to anticholinesterases--a mechanistic review. Toxicol Lett. 1998 Dec 28;102-103:527-33. A single dose of sarin or repeated doses of metrifonate or mevinphos, have produced only transient adverse effects at doses causing substantial acetylcholinesterase inhibition. |
0(0,0,0,0) | Details |
| 139320 | Brown HR, Sharma RP: Synaptosomal triphosphatase (ATPase) inhibition by organophosphates. Experientia. 1976 Dec 15;32(12):1540-2. Chicken spinal cord triphosphatases (both Na+, K+ stimulated and ouabain insensitive) were inhibited by tri-o-tolyl (TOTP, a organophosphate which is not a cholinesterase inhibitor) and mevinphos (a non- compound but inhibitor of cholinesterases). |
0(0,0,0,0) | Details |
| 565668 | Obersteiner EJ, Sharma RP: Evaluation of cytotoxic responses caused by selected organophosphorus esters in chick sympathetic ganglia cultures. Can J Comp Med. 1978 Jan;42(1):80-8. Concentrations that produced half-maximal effects ranged from 1 x 10 (-6) M (severely toxic) for methylparathian, diazinon, paraoxon, mevinphos, diisopropylfluorophosphate, tri-o-tolyl and its mixed isomers to a 1 x 10 (-3) M (intermediate) for malathion, leptophos, coumaphos, mono- and dicrotophos. |
0(0,0,0,0) | Details |
| 7097799 | Skinner CS, Kilgore WW: Acute dermal toxicities of various organophosphate insecticides in mice. J Toxicol Environ Health. 1982 Mar;9(3):491-7. Cholinesterase ED50 values roughly agreed with LD50 values for mevinphos, parathion, methyl parathion, and azinphos-methyl, but diazinon appeared much more inhibitory of blood than neuronal cholinesterase. |
88(1,1,2,3) | Details |
| 8714219 | Cochran RC, Formoli TA, Silva MH, Kellner TP, Lewis CM, Pfeifer KF: Risks from occupational and dietary exposure to mevinphos. . Rev Environ Contam Toxicol. 1996;146:1-24. The principal toxic effects of mevinphos, both short- and long term, were due to inhibition of cholinesterase activity. |
81(1,1,1,1) | Details |
| 4713487 | Sharma RP, Shupe JL, Potter JR: Tissue cholinesterase inhibition by 2-carbomethoxy-1-methylvinyl dimethyl (mevinphos). Toxicol Appl Pharmacol. 1973 Apr;24(4):645-52. |
81(1,1,1,1) | Details |
| 233186 | Verberk MM, Salle HJ: Neurological effects and cholinesterase inhibition in man by subacute administration of mevinphos. Act Nerv Super. 1977 Jul;19 Suppl 2:333-4. |
81(1,1,1,1) | Details |
| 7245190 | Carricaburu P, Lacroix R, Lacroix J: Electroretinographic study of the white mouse intoxicated by organo- mevinphos and malathion. Toxicol Eur Res. 1981 Mar;3(2):87-91. Evidence is given that the organo-phosphates mevinphos and malathion perturb the retinal functioning of the white mouse by acting 1. directly on the photoreceptors; 2. by a synaptolytic effect due to the inhibition of cholinesterases; 3. likely by a damage of the bipolar and/or the ganglion neurones. |
81(1,1,1,1) | Details |