Protein Information

Name CYP2B6
Synonyms CPB 6; CPB6; CYP2B; CYP2B protein; CYP2B6; CYPIIB 6; CYPIIB6; Cytochrome P450 2B6…

Compound Information

Name pyrethrins
CAS pyrethrins

Reference List

PubMed Abstract RScore(About this table)
18022748 Price RJ, Giddings AM, Scott MP, Walters DG, Capen CC, Osimitz TG, Lake BG: Effect of Pyrethrins on cytochrome P450 forms in cultured rat and human hepatocytes. Toxicology. 2008 Jan 14;243(1-2):84-95. Epub 2007 Oct 7.

In human hepatocytes Pyrethrins and Phenobarbital induced both testosterone 6beta-hydroxylase activity and CYP3A4 mRNA levels and also increased CYP2B6 mRNA levels.
6(0,0,1,1) Details
19326768 Das PC, Streit TM, Cao Y, Rose RL, Cherrington N, Ross MK, Wallace AD, Hodgson E: Pyrethroids: cytotoxicity and induction of CYP isoforms in human hepatocytes. Drug Metabol Drug Interact. 2008;23(3-4):211-36.


At 100 microM deltamethrin 2-3 fold induction of CYP1A1 and CYP2B6 mRNA was observed, while at the same time an approximately 25-fold induction of CYP3A4 was noted.
2(0,0,0,2) Details