Name | CYP2B6 |
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Synonyms | CPB 6; CPB6; CYP2B; CYP2B protein; CYP2B6; CYPIIB 6; CYPIIB6; Cytochrome P450 2B6… |
Name | pyrethrins |
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CAS | pyrethrins |
PubMed | Abstract | RScore(About this table) | |
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18022748 | Price RJ, Giddings AM, Scott MP, Walters DG, Capen CC, Osimitz TG, Lake BG: Effect of Pyrethrins on cytochrome P450 forms in cultured rat and human hepatocytes. Toxicology. 2008 Jan 14;243(1-2):84-95. Epub 2007 Oct 7. In human hepatocytes Pyrethrins and Phenobarbital induced both 6beta-hydroxylase activity and CYP3A4 mRNA levels and also increased CYP2B6 mRNA levels. |
6(0,0,1,1) | Details |
19326768 | Das PC, Streit TM, Cao Y, Rose RL, Cherrington N, Ross MK, Wallace AD, Hodgson E: Pyrethroids: cytotoxicity and induction of CYP isoforms in human hepatocytes. Drug Metabol Drug Interact. 2008;23(3-4):211-36. At 100 microM deltamethrin 2-3 fold induction of CYP1A1 and CYP2B6 mRNA was observed, while at the same time an approximately 25-fold induction of CYP3A4 was noted. |
2(0,0,0,2) | Details |