| Name | P450scc |
|---|---|
| Synonyms | CYP11A; CYP11A1; CYPXIA 1; CYPXIA1; Cholesterol 20 22 desmolase; Cholesterol desmolase; Cholesterol monooxygenase (side chain cleaving); Cholesterol side chain cleavage enzyme… |
| Name | pyrethrins |
|---|---|
| CAS | pyrethrins |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19683566 | Zhang H, Wang H, Ji YL, Ning H, Yu T, Zhang C, Zhang Y, Zhao XF, Wang Q, Liu P, Meng XH, Xu DX: Lactational fenvalerate exposure permanently impairs testicular development and spermatogenesis in mice. Toxicol Lett. 2009 Dec 1;191(1):47-56. Epub 2009 Aug 14. Additional experiment showed that lactational fenvalerate exposure markedly reduced mRNA and protein levels of testicular P450scc, a (T) synthesis enzyme. |
3(0,0,0,3) | Details |
| 19892000 | Fei J, Qu JH, Ding XL, Xue K, Lu CC, Chen JF, Song L, Xia YK, Wang SL, Wang XR: Fenvalerate inhibits the growth of primary cultured rat preantral ovarian follicles. Toxicology. 2010 Jan 12;267(1-3):1-6. Epub 2009 Nov 3. And then the morphous was assessed by conventional light microscopy, steroid hormones were measured by RIA, and the expressions of steroidogenic acute regulatory protein (StAR) and cytochrome P450 side-chain cleavage enzyme (P450scc) were monitored by real-time quantitative PCR analysis. |
3(0,0,0,3) | Details |
| 15907653 | Chen J, Chen H, Liu R, He J, Song L, Bian Q, Xu L, Zhou J, Xiao H, Dai G, Chang HC, Wang X: Effects of fenvalerate on production in cultured rat granulosa cells. Reprod Toxicol. 2005 Jul-Aug;20(2):195-202. Expression of P450 side chain cleavage enzyme (P450scc) and steroidogenic acute regulatory protein (StAR) were monitored by real-time PCR and Western blotting. |
3(0,0,0,3) | Details |
| 18053657 | Qu JH, Hong X, Chen JF, Wang YB, Sun H, Xu XL, Song L, Wang SL, Wang XR: Fenvalerate inhibits production through cAMP-dependent signal pathway. Toxicol Lett. 2008 Jan 4;176(1):31-9. Epub 2007 Sep 21. In addition, fenvalerate decreased steroidogenic acute regulatory protein (StAR) mRNA and protein levels, and also profoundly inhibited the activity of P450 side chain cleavage enzyme (P450scc) which was consistent with the decreased expression of P450scc mRNA and protein in MLTC-1 cells. |
2(0,0,0,2) | Details |