Protein Information

Name ATPase
Synonyms ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1…

Compound Information

Name pyrethrins
CAS pyrethrins

Reference List

PubMed Abstract RScore(About this table)
12615099 Kakko I, Toimela T, Tahti H: The synaptosomal membrane bound ATPase as a target for the neurotoxic effects of pyrethroids, permethrin and cypermethrin. Chemosphere. 2003 May;51(6):475-80.

6(0,0,0,6) Details
15652757 Grosman N, Diel F: Influence of pyrethroids and piperonyl butoxide on the Ca (2+)-ATPase activity of rat brain synaptosomes and leukocyte membranes. Int Immunopharmacol. 2005 Feb;5(2):263-70.

5(0,0,0,5) Details
15033010 Chen L, Shi N, Dong J, Li T, Chen D: [Effects of estradiol on deltamethrin-induced neurotoxicity in rat cerebro-cortical synaptosomes]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2004 Feb;22(1):22-5.


OBJECTIVE: To investigate the neuroprotective effect of estradiol on the release of excitatory amino acid (EAAs) mediator, and the activity of ATPase in cerebro-cortical synaptosome membrane of rats exposed to deltamethrin.
4(0,0,0,4) Details
14989895 He J, Chen JF, Liu R, Wang YB, Wang XR: [Effect of fenvalerate on the ovarian calcium homeostasis and the serum steroid hormone]. Zhonghua Yu Fang Yi Xue Za Zhi. 2004 Jan;38(1):18-21.


The activity of ovarian Ca (2+)-ATPase and phosphorylase A (P-a) and the contents of calmodulin (CaM) were assessed after a 30-day Fen exposure.
2(0,0,0,2) Details
17490606 Sreeramulu K, Liu R, Sharom FJ: Interaction of insecticides with mammalian P-glycoprotein and their effect on its transport function. Biochim Biophys Acta. 2007 Jul;1768(7):1750-7. Epub 2007 Apr 5.


All the pesticides stimulated P-glycoprotein ATPase activity, with maximum stimulation of up to 213% in a detergent-solubilized preparation, and up to 227% in reconstituted liposomes.
2(0,0,0,2) Details
12524023 Das BK, Mukherjee SC: Toxicity of cypermethrin in Labeo rohita fingerlings: biochemical, enzymatic and haematological consequences. Comp Biochem Physiol C Toxicol Pharmacol. 2003 Jan;134(1):109-21.


Succinate dehydrogenase and ATPase activities were depleted in brain, kidney and liver.
1(0,0,0,1) Details
15454122 Garg UK, Pal AK, Jha GJ, Jadhao SB: Haemato-biochemical and immuno-pathophysiological effects of chronic toxicity with synthetic pyrethroid, organophosphate and chlorinated pesticides in broiler chicks. Int Immunopharmacol. 2004 Dec 15;4(13):1709-22.


The total ATPase activity was enhanced (P <0.01) in fenvalerate and monocrotophos than birds in control group.
1(0,0,0,1) Details