| Name | TRPV3 |
|---|---|
| Synonyms | TRPV 3; TRPV3; Transient receptor potential cation channel subfamily V member 3; VRL 3; VRL3; Vanilloid receptor like 3; Vanilloid receptor like protein 3; Vanilloid receptor related Osmotically activated channel protein… |
| Name | eugenol |
|---|---|
| CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20086034 | Earley S, Gonzales AL, Garcia ZI: A dietary agonist of transient receptor potential cation channel V3 elicits endothelium-dependent vasodilation. Mol Pharmacol. 2010 Apr;77(4):612-20. Epub 2010 Jan 19. Carvacrol causes concentration-dependent increases in the intracellular [Ca (2+)] of native cerebral artery endothelial cells and is more potent (EC (50) = 34 microM) than the TRPA1 agonist (EC (50) = 400 microM) or the TRPV3 agonist eugenol (EC (50) = 2.3 mM). |
85(1,1,1,5) | Details |
| 16617338 | Xu H, Delling M, Jun JC, Clapham DE: Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels. Nat Neurosci. 2006 May;9(5):628-35. Epub 2006 Apr 16. Here we show that TRPV3 is strongly activated and sensitized by carvacrol, and eugenol. |
84(1,1,1,4) | Details |
| 19135721 | Parnas M, Peters M, Dadon D, Lev S, Vertkin I, Slutsky I, Minke B: Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels. Cell Calcium. 2009 Mar;45(3):300-9. Epub 2009 Jan 9. We also show that additional activators of TRPV3, eugenol, and are all inhibitors of the TRPL channel. |
32(0,1,1,2) | Details |