| Name | FMO1 |
|---|---|
| Synonyms | Dimethylaniline monooxygenase 1; Dimethylaniline monooxygenase [N oxide forming] 1; Dimethylaniline oxidase 1; FMO 1; FMO1; Fetal hepatic flavin containing monooxygenase 1; Flavin containing monooxygenase 1; Dimethylaniline monooxygenase [N oxide forming] 1s… |
| Name | methiocarb |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15547051 | Furnes B, Schlenk D: Extrahepatic metabolism of and organophosphate thioether compounds by the flavin-containing monooxygenase and cytochrome P450 systems. Drug Metab Dispos. 2005 Feb;33(2):214-8. Epub 2004 Nov 16. The relative contribution of FMO1 and FMO3 to the sulfoxidation of carbophenothion, demeton-O, ethiofencarb, fonofos, and methiocarb also was investigated by using baculovirus-expressed recombinant proteins. |
8(0,0,1,3) | Details |
| 14977868 | Usmani KA, Karoly ED, Hodgson E, Rose RL: In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily. Drug Metab Dispos. 2004 Mar;32(3):333-9. Among 16 cDNA-expressed human P450 isoforms and 3 human FMO isoforms examined, the following isoforms and their polymorphisms had the highest rates for sulfoxidation, as follows: phorate, CYP1A2, 3A4, 2B6, 2C9*1, 2C18, 2C19, 2D6*1, and FMO1; disulfoton, CYP1A2, 3A4, 2B6, 2C9*1, 2C9*2, 2C18, 2C19, 2D6*1, and FMO1; sulprofos, CYP1A1, 1A2, 3A4, 2C9*1, 2C9*2, 2C9*3, 2C18, 2C19, 2D6*1, and FMO1; methiocarb, CYP1A1, 1A2, 3A4, 2B6, 2C9*1, 2C19, 2D6*1, and FMO1. |
6(0,0,1,1) | Details |