Name | vesicular GABA transporter |
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Synonyms | GABA and glycine transporter; SLC32A1; Solute carrier family 32 member 1; VGAT; VIAAT; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter; bA122O1.1… |
Name | strychnine |
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CAS | strychnidin-10-one |
PubMed | Abstract | RScore(About this table) | |
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17418495 | Fujii M, Arata A, Kanbara-Kume N, Saito K, Yanagawa Y, Obata K: Respiratory activity in brainstem of fetal mice lacking vesicular GABA transporter. Neuroscience. 2007 May 25;146(3):1044-52. Epub 2007 Apr 5. Strychnine reversed inspiratory-phase hyperpolarization to large depolarization in expiratory neurons. |
decarboxylase 65/67 and 2(0,0,0,2) | Details |
11487628 | Dumoulin A, Triller A, Dieudonne S: IPSC kinetics at identified GABAergic and mixed GABAergic and glycinergic synapses onto cerebellar Golgi cells. J Neurosci. 2001 Aug 15;21(16):6045-57. Double immunocytochemical stainings demonstrate that GABAergic and glycinergic markers are coexpressed in Lugaro cell axonal varicosities, together with the mixed vesicular inhibitory amino acid transporter. |
1(0,0,0,1) | Details |
12401451 | Meier J, Juttner R, Kirischuk S, Grantyn R: Synaptic anchoring of glycine receptors in developing collicular neurons under control of metabotropic glutamate receptor activity. Mol Cell Neurosci. 2002 Oct;21(2):324-40. Two distinct stages of inhibitory synaptogenesis in cultured collicular neurons were defined on the basis of strychnine sensitivity of IPSCs, presence of EPSCs, KCC2 expression, and transmitter-induced Ca (2+) responses. In the absence of KCC2 and glutamatergic transmission, newborn VIAAT-labeled boutons contained GlyT2, released and accumulated postsynaptic gephyrin and GlyRs. |
1(0,0,0,1) | Details |
15555918 | Danglot L, Rostaing P, Triller A, Bessis A: Morphologically identified glycinergic synapses in the hippocampus. . Mol Cell Neurosci. 2004 Dec;27(4):394-403. Inhibitory transmission in the hippocampus is predominantly GABAergic, but electrophysiological data evidenced strychnine-sensitive -induced currents. Synaptic GlyRs were apposed to glycinergic boutons characterized by the expression of the vesicular and the plasma membrane transporters of (VIAAT and GlyT2, respectively). |
1(0,0,0,1) | Details |
18815261 | Rousseau F, Aubrey KR, Supplisson S: The transporter GlyT2 controls the dynamics of synaptic vesicle refilling in inhibitory spinal cord neurons. J Neurosci. 2008 Sep 24;28(39):9755-68. At inhibitory synapses, and are accumulated into synaptic vesicles by the same vesicular transporter VGAT/VIAAT (vesicular GABA transporter/vesicular inhibitory amino acid transporter), enabling a continuum of and mixed phenotypes. |
1(0,0,0,1) | Details |
15746915 | Gillespie DC, Kim G, Kandler K: Inhibitory synapses in the developing auditory system are glutamatergic. Nat Neurosci. 2005 Mar;8(3):332-8. Epub 2005 Jan 30. Immunohistochemical studies demonstrate synaptic colocalization of the vesicular glutamate transporter 3 with the vesicular GABA transporter, indicating that and are released from single MNTB terminals. |
1(0,0,0,1) | Details |