| Name | coproporphyrinogen oxidase |
|---|---|
| Synonyms | COX; HCP; CPO; CPOX; CPX; Coprogen oxidase; Coproporphyrinogen oxidase; Coproporphyrinogen oxidase variant… |
| Name | hexachlorobenzene |
|---|---|
| CAS | 1,2,3,4,5,6-hexachlorobenzene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19482825 | Sopena YE, Ferramola de Sancovich AM, Sancovich HA: Hexachlorobenzene treatment on hepatic mitochondrial function parameters and intracellular coproporphyrinogen oxidase location. Int J Toxicol. 2008 Nov;27(6):455-65. |
88(1,1,2,3) | Details |
| 2079105 | Adjarov DG: Decreased activity of liver coproporphyrinogen oxidase in hexachlorobenzene-induced porphyria. Exp Pathol. 1990;40(2):117-22. |
12(0,0,2,2) | Details |
| 16084099 | Cooper CL, Stob CM, Jones MA, Lash TD: Metabolism of pentacarboxylate porphyrinogens by highly purified human coproporphyrinogen oxidase: further evidence for the existence of an abnormal pathway for heme biosynthesis. Bioorg Med Chem. 2005 Nov 15;13(22):6244-51. Epub 2005 Aug 3. Although 5dab is a slightly poorer substrate than copro'gen-III, these results support the hypothesis that an abnormal route for heme biosynthesis is possible in humans suffering from PCT or related syndromes such as hexachlorobenzene poisoning. |
2(0,0,0,2) | Details |