| Name | anticholinesterase |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | monocrotophos |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3350449 | Peiris JB, Fernando R, De Abrew K: Respiratory failure from severe organophosphate toxicity due to absorption through the skin. Forensic Sci Int. 1988 Feb;36(3-4):251-3. The plasma cholinesterase levels were within 37.5-50% of normal even on the 20th day indicating severe exposure. A 32-year-old man was admitted to a peripheral hospital following assault with a 100-ml bottle of insecticide called Monocrotophos, an organophosphate. |
1(0,0,0,1) | Details |
| 1190841 | Ware GW, Morgan DP, Estesen BJ, Cahill WP: Establishment of reentry intervals for organophosphate-treated cotton fields based on human data: III. 12 To 72 hours post-treatment exposure to monocrotophos, ethyl- and methyl parathion. Arch Environ Contam Toxicol. 1975;3(3):289-306. Personal exposure to pesticide was evaluated from contamination of skin, clothing, and ambient air, while actual absorption of chemical was assessed from pesticide concentration in blood, urinary metabolite excretion, and effects on blood cholinesterase activities. |
1(0,0,0,1) | Details |
| 4479741 | Voss G: A contribution to the comparative biochemistry of vertebrate serum cholinesterases. Arch Toxicol. 1974;32(3):181-7. |
1(0,0,0,1) | Details |
| 420356 | Morse DL, Baker EL, Landrigan PJ: Cut flowers: a potential pesticide hazard. Am J Public Health. 1979 Jan;69(1):53-6. Azodrin (monocrotophos) was the most important contaminant with levels of 7.7--4,750 ppm detected in nine lots. |
0(0,0,0,0) | Details |
| 7406551 | Rao RR, Quadros F, Mazmudar RM, Marathe MR, Gangoli SD: Toxicological effects of aerial application of monocrotophos. . Arch Environ Contam Toxicol. 1980;9(4):473-81. |
0(0,0,0,0) | Details |
| 3022432 | Kummer R, van Sittert NJ: Field studies on health effects from the application of two organophosphorus insecticide formulations by hand-held ULV to cotton. Toxicol Lett. 1986 Oct;33(1-3):7-24. The second study took place in Indonesia with a 20% monocrotophos formulation in a mixture of a glycol and a glycol ether. |
0(0,0,0,0) | Details |
| 1267489 | Guthrie FE, Domanski JJ, Chasson AL, Bradway DE, Monroe RJ: Human subject experiments to estimate reentry periods for monocrotophos-treated tobacco. Arch Environ Contam Toxicol. 1976;4(2):217-25. |
0(0,0,0,0) | Details |
| 15454122 | Garg UK, Pal AK, Jha GJ, Jadhao SB: Haemato-biochemical and immuno-pathophysiological effects of chronic toxicity with synthetic pyrethroid, organophosphate and chlorinated pesticides in broiler chicks. Int Immunopharmacol. 2004 Dec 15;4(13):1709-22. Haemato- biochemical and immuno-pathophysiological changes following feeding of broiler chicks with 20 ppm fenvalerate (synthetic pyrethroid, SP), 2 ppm monocrotophos (organophosphate, OP) and 2 ppm endosulfan (chlorinated hydrocarbon, CH) were studied. |
0(0,0,0,0) | Details |
| 2100760 | van Sittert NJ, Dumas EP: Field study on exposure and health effects of an organophosphate pesticide for maintaining registration in the Philippines. Med Lav. 1990 Nov-Dec;81(6):463-73. To support the continued use and the registration of monocrotophos, a field study was conducted at Calauan, Laguna, The Philippines, to assess exposure and the resulting health risk to 21 spraymen applying monocrotophos to rice crop by knapsack spraying during 3 consecutive days. |
0(0,0,0,0) | Details |
| 6154073 | Riskallah MR: Reduced sensitivity of cholinesterase as a factor of resistance in leptophos selected strain in the Egyptian cotton leafworm. J Environ Sci Health B. 1980;15(2):181-92. On the other hand, there was a considerable degree of insensitivity of cholinesterase to inhibition by leptophos-oxon, methyl paraoxon, cyolane, cytrolane, monocrotophos, and matacil in larvae of the resistant strain. |
85(1,1,1,5) | Details |
| 595013 | Verberk MM: Incipient cholinesterase inhibition in volunteers ingesting monocrotophos or mevinphos for one month. Toxicol Appl Pharmacol. 1977 Nov;42(2):345-50. |
81(1,1,1,1) | Details |
| 12177756 | Parma De Croux MJ, Loteste A, Cazenave J: Inhibition of plasma cholinesterase and acute toxicity of monocrotophos in a neotropical fish Prochilodus lineatus (pisces, curimatidae). Bull Environ Contam Toxicol. 2002 Sep;69(3):356-63. |
81(1,1,1,1) | Details |
| 3413031 | Sandhu HS, Malik JK: Subacute toxicity of monocrotophos and its influence on circulating enzymes of Bubalus bubalis. Pharmacol Toxicol. 1988 May;62(5):290-2. Monocrotophos at both doses caused significant inactivation of erythrocyte cholinesterase (29.4-50.8%) and caused significant elevation in the serum levels of and alanine aminotransferases. |
81(1,1,1,1) | Details |
| 1417899 | Swamy KV, Ravikumar R, Mohan PM: Changes in cholinesterase system in different brain areas during the development of behavioral tolerance to monocrotophos toxicity in male albino rats. Biochem Int. 1992 Aug;27(4):661-9. |
21(0,0,3,6) | Details |
| 1868785 | Siddiqui MK, Rahman MF, Mustafa M, Rahman MF, Bhalerao UT: A comparative study of blood changes and brain acetylcholinesterase inhibition by monocrotophos and its analogues in rats. Ecotoxicol Environ Saf. 1991 Jun;21(3):283-9. In vitro studies with partially purified preparations of rat brain cholinesterase revealed that monocrotophos was the most potent anticholinesterase agent, followed by RPR-II and RPR-V. |
7(0,0,1,2) | Details |
| 7809420 | Schulze-Rosario C, Loosli R: Monocrotophos--worker safety. Rev Environ Contam Toxicol. 1994;139:47-57. Monitoring data on field-worker exposure studies show that prolonged or continued use of monocrotophos in plant protection may lead to significant dermal exposure with an impact on cholinesterase activity. |
6(0,0,1,1) | Details |
| 12597563 | Loteste A, Cazenave J, Parma de Croux MJ: Recovery of plasmatic cholinesterase activity in a neotropical fish Prochilodus lineatus (Pisces, Curimatidae) exposed to organophosphorous pesticides. J Environ Biol. 2002 Jul;23(3):225-9. Fish were exposed 12 h to a sublethal concentration of 1 mg/l of monocrotophos, and immediately placing in clean water during 12, 24, 48 and 96 h to detoxification. |
3(0,0,0,3) | Details |
| 8349949 | Casale GP, Vennerstrom JL, Bavari S, Wang TL: Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected and organophosphate insecticides and congeners of carbaryl. Immunopharmacol Immunotoxicol. 1993 Mar-Jun;15(2-3):199-215. The anticholinesterase (antiCHE) insecticides, a large family of pesticides used extensively throughout the world, inhibit serine hydrolases by carbamylating or phosphorylating a serine residue at the catalytic site. The order of potency for T cell inhibition was carbaryl = dichlorvos > methiocarb > carbofuran > paraoxon > mevinphos > aldicarb = monocrotophos. |
1(0,0,0,1) | Details |
| 3323058 | Pilo B, Mehan SP: Effect of cholinesterase inhibitors on and insulin induced uptake and certain hepatic enzymes in pigeon liver: an in vitro study. Indian J Physiol Pharmacol. 1987 Jul-Sep;31(3):159-69. Monocrotophos, acothione (organophosphorus compound) and prostigmine are known inhibitors of acetylcholinesterase (AChE). |
1(0,0,0,1) | Details |
| 2593091 | Audegond L, Catez D, Foulhoux P, Fournex R, Le Rumeur C, L'Hotellier M, Stepniewski JP: [Potentiation of deltamethrin toxicity by organophosphorus insecticides] . J Toxicol Clin Exp. 1989 May-Jun;9(3):163-76. Others (methyl-parathion, acephate, phosphamidon, monocrotophos) have no such effects, even if they have a very high intrinsic toxicity. Cholinesterase inhibitors of the group are ineffective. |
1(0,0,0,1) | Details |
| 20021020 | Das GP, Jamil K, Rahman MF: Effect of four organophosphorus compounds on human blood acetylcholinesterase: in vitro studies. Toxicol Mech Methods. 2006;16(8):455-9. The aim of the study was to determine the IC50 concentration of the pesticides monocrotophos, chlorpyrifos, profenofos, and acephate as inhibitors of AChE. Cholinesterase was spectrophotometrically measured using acetylthiocholine iodide (AChI) as substrate and dithiobisnitrobenzoic acid (DTNB) as the coloring agent using different aliquots of the pesticides. |
1(0,0,0,1) | Details |
| 7523071 | Qadri YH, Swamy AN, Rao JV: Species differences in brain acetylcholinesterase response to monocrotophos in vitro. Ecotoxicol Environ Saf. 1994 Jun;28(1):91-8. Species-related differences in sensitivity to acute intoxication by anticholinesterase (anti-ChE) compounds have been attributed, in large part, to differences in the kinetics of inhibition of acetylcholinesterase (AChE: EC 3.1.1.7) in vitro. |
1(0,0,0,1) | Details |
| 847753 | Pickering CE, Pickering RG: The interference by erythrocyte "acetylthiocholinesterase" in the estimation of the blood cholinesterase activity of the chicken. Toxicol Appl Pharmacol. 1977 Feb;39(2):229-37. |
1(0,0,0,1) | Details |