Protein Information

Name butyrylcholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

Name chloroform
CAS trichloromethane

Reference List

PubMed Abstract RScore(About this table)
17518351 Ahmad B, Shah SM, Bashir S, Shah J: Enzyme inhibition activities of Andrachne cardifolia Muell. J Enzyme Inhib Med Chem. 2007 Apr;22(2):235-8.

The crude methanolic extract and various fractions of Andrachne cardifolia Muell, including chloroform, ethyl acetate and n-butanol fractions were subjected to in vitro enzyme inhibition activity against acetylcholinesterase, butyrylcholinesterase, lipoxygenase and urease enzymes.
32(0,1,1,2) Details
19384728 Orhan I, Ozcelik B, Aslan S, Kartal M, Karaoglu T, Sener B, Terzioglu S, Iqbal Choudhary M: In vitro biological activity screening of Lycopodium complanatum L. ssp. chamaecyparissus (A. Nat Prod Res. 2009;23(6):514-26.

This article reports the results of selected biological activities, including anticholinesterase, antioxidant, antibacterial, antifungal and antiviral properties, of the petroleum ether, chloroform and methanol extracts as well as the alkaloid fraction of Lycopodium complanatum L. ssp. chamaecyparissus (A.
7(0,0,1,2) Details
18237025 Khan H, Khan MA, Hussan I: Enzyme inhibition activities of the extracts from rhizomes of Gloriosa superba Linn (Colchicaceae). J Enzyme Inhib Med Chem. 2007 Dec;22(6):722-5.

The crude extract and its subsequent fractions including chloroform, ethyl acetate, n-butanol and aqueous were screened against lipoxygenase, actylcholinesterase, butyrylcholinesterase and urease.
6(0,0,1,1) Details
18237027 Ahmad B, Mukarram Shah SM, Khan H, Hassan Shah SM: Enzyme inhibition activities of Teucrium royleanum. J Enzyme Inhib Med Chem. 2007 Dec;22(6):730-2.

The crude methanolic extract and chloroform, ethyl acetate and n-butanol fractions of Teucrium royleanum were examined as inhibitors of actylcholinesterase, butyrylcholinesterase, lipoxygenase and urease.
32(0,1,1,2) Details
19269215 Tennakoon S, Perera B, Haturusinghe L: Intentional poisoning cases of animals with anticholinesterase pesticide-carbofuran in Sri Lanka. Leg Med. 2009 Apr;11 Suppl 1:S500-2. Epub 2009 Mar 6.

The liquid-liquid extraction with chloroform was reproducible and sensitive.
2(0,0,0,2) Details
18787788 Fatima I, Ahmad I, Anis I, Malik A, Afza N, Iqbal L, Latif M: New butyrylcholinesterase inhibitory steroid and peroxy acid from Leucas urticifolia. Arch Pharm Res. 2008 Aug;31(8):999-1003. Epub 2008 Sep 12.

A new steroid leucisterol (1) and a new peroxy acid urticic acid (2) along with methoxybenzyl benzoate (3), 4-hydroxy benzoic acid (4), beta-sitosterol (5), and ursolic acid (6), have been isolated from the chloroform soluble fraction of the whole plant of Leucas urticifolia.
2(0,0,0,2) Details
18618318 Sultana N, Ata A: Oleanolic acid and related derivatives as medicinally important compounds. J Enzyme Inhib Med Chem. 2008 Dec;23(6):739-56.

Oleanolic acid has been isolated from chloroform extract of Olea ferruginea Royle after removal of organic bases and free acids.
The aim of this review is to update current knowledge on oleanolic acid and its natural and semisynthetic analogs, focussing on its cytotoxic, antitumer, antioxidant, anti-inflamatory, anti-HIV, acetyl cholinesterase, alpha-glucosidase, antimicrobial, hepatoprotective, anti-inflammatory, antipruritic, spasmolytic activity, anti-angiogenic, antiallergic, antiviral and immunomodulatory activities.
1(0,0,0,1) Details
18803226 Kim SJ, Lee K: Extracts of Liriopsis tuber protect AMPA induced brain damage and improve memory with the activation of insulin receptor and ERK I/II. Phytother Res. 2008 Nov;22(11):1450-7.

LT was extracted with 70% methanol and subsequently fractionated into chloroform (fraction C), chloroform/methanol-(3:1) (fraction CM), methanol-soluble (fraction M) and methanol-insoluble, water-soluble fractions (fraction A).
In addition, ERK I/II were stimulated and cholinesterase activities were inhibited by fractions T, C, M and A in the rat hippocampus.
2(0,0,0,2) Details