Protein Information

Name vascular endothelial growth factor receptor 1
Synonyms FLT; Tyrosine protein kinase receptor; FLT1; FMS related tyrosine kinase 1; FRT; Flt 1; Fms like tyrosine kinase 1; Fms related tyrosine kinase 1 (Vascular endothelial growth factor/vascular permeability factor receptor) variant…

Compound Information

Name chloroform
CAS trichloromethane

Reference List

PubMed Abstract RScore(About this table)
18484531 Ponticelli S, Braca A, De Tommasi N, De Falco S: Competitive ELISA-based screening of plant derivatives for the inhibition of VEGF family members interaction with vascular endothelial growth factor receptor 1. Planta Med. 2008 Mar;74(4):401-6.

Several fractions of the N-butanol extract of Pteleopsis suberosa leaves and of the chloroform extract of Parinari campestris leaves demonstrated by a bioassay-guided fractionation an evident inhibition of VEGF-A or placental growth factor (PlGF) interaction with Flt-1, with an inhibition over 50 % in particular for the VEGF-A/Flt-1 interaction at a concentration of 100 microg/mL.
35(0,1,1,5) Details