| Name | PC3 |
|---|---|
| Synonyms | CBX 8; PC3; CBX8; Chromobox homolog 8; Chromobox homolog 8 polycomb 3; Chromobox protein homolog 8; HPC 3; HPC3… |
| Name | chloroform |
|---|---|
| CAS | trichloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19270378 | Yang SO, Kim MS, Liu KH, Auh JH, Kim YS, Kwon DY, Choi HK: Classification of fermented soybean paste during fermentation by 1H nuclear magnetic resonance spectroscopy and principal component analysis. Biosci Biotechnol Biochem. 2009 Mar 23;73(3):502-7. Epub 2009 Mar 7. In addition, the (1) H NMR spectra of chloroform extracts were separated mainly by a combination of PC1 and PC3, which accounted for 72.6% of the variance. |
6(0,0,1,1) | Details |
| 17728215 | Singh LS, Berk M, Oates R, Zhao Z, Tan H, Jiang Y, Zhou A, Kirmani K, Steinmetz R, Lindner D, Xu Y: Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer. J Natl Cancer Inst. 2007 Sep 5;99(17):1313-27. Epub 2007 Aug 28. In vitro, expression of OGR1, but not GPR4, inhibited cell migration (mean percentage of cells migrated, 30.2% versus 100%, difference = 69.8%, 95% CI = 63.0% to 75.9%; P <.001) via increased expression of G alpha (i1) and the secretion of a chloroform/-extractable heat-insensitive factor into the conditioned medium through a PTX-sensitive pathway. METHODS: We used an orthotopic mouse metastasis model, in which we injected PC3 metastatic human prostate cancer cells stably transfected with empty vector (vector-PC3) or OGR1-expressing vector (OGR1-PC3) into the prostate lobes of athymic or NOD/SCID mice (n = 3-8 mice per group). |
3(0,0,0,3) | Details |
| 19399188 | Lavhale MS, Kumar S, Mishra SH, Sitasawad SL: A novel triterpenoid isolated from the root bark of Ailanthus excelsa Roxb (Tree of Heaven), AECHL-1 as a potential anti-cancer agent. PLoS One. 2009;4(4):e5365. Epub 2009 Apr 28. BACKGROUND: We report here the isolation and characterization of a new compound Ailanthus excelsa chloroform extract-1 (AECHL-1) (C (29) H (36) O (10); molecular weight 543.8) from the root bark of Ailanthus excelsa Roxb. PRINCIPAL FINDINGS: AECHL-1 treatment for 12 to 48 hr inhibited cell proliferation and induced death in B16F10, MDA-MB-231, MCF-7, and PC3 cells with minimum growth inhibition in normal HEK 293. |
2(0,0,0,2) | Details |