Protein Information

Name PI3K
Synonyms GRB 1; PI3K; GRB1; PI3 kinase p85 subunit alpha; Phosphatidyl inositol 3 kinase associated p85 alpha; Phosphatidylinositol 3 kinase regulatory subunit alpha; PtdIns 3 kinase p85 alpha…

Compound Information

Name chloroform
CAS trichloromethane

Reference List

PubMed Abstract RScore(About this table)
19744549 Kumar R, Balaji S, Uma TS, Sehgal PK: Fruit extracts of Momordica charantia potentiate glucose uptake and up-regulate Glut-4, PPAR gamma and PI3K. J Ethnopharmacol. 2009 Dec 10;126(3):533-7. Epub 2009 Sep 8.

Effects of aqueous and chloroform extracts of Momordica charantia fruit on glucose uptake and up-regulation of glucose transporter (Glut-4), peroxisome proliferator activator receptor gamma (PPAR gamma) and phosphatidylinositol-3 kinase (PI3K), were investigated to show its efficacy as a hypoglycaemic agent.
65(0,2,2,5) Details
19272638 Hayes MP, Douglas W, Ellenson LH: Molecular alterations of EGFR and PIK3CA in uterine serous carcinoma. . Gynecol Oncol. 2009 Jun;113(3):370-3. Epub 2009 Mar 9.

This study sought to evaluate primary USC tumors for molecular alterations in epidermal growth factor receptor (EGFR) and the recently characterized oncogene PIK3CA, which encodes the catalytic p110-alpha subunit of phosphatidylinositol 3-kinase (PI3K) and thus activates the AKT-mTOR oncogenic pathway.
For mutational analysis, neoplastic tissue was microdissected and DNA was extracted with phenol-chloroform.
2(0,0,0,2) Details