Protein Information

Name protein tyrosine phosphatase 1B
Synonyms PTP 1B; PTP1B; PTPN 1; PTPN1; Protein tyrosine phosphatase 1B; Tyrosine protein phosphatase non receptor type 1; Protein tyrosine phosphatase 1Bs; Tyrosine protein phosphatase non receptor type 1s

Compound Information

Name chloroform
CAS trichloromethane

Reference List

PubMed Abstract RScore(About this table)
19846295 Hoang DM, Ngoc TM, Dat NT, Ha do T, Kim YH, Luong HV, Ahn JS, Bae K: Protein tyrosine phosphatase 1B inhibitors isolated from Morus bombycis. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6759-61. Epub 2009 Oct 7.

Bioassay-guided fractionation of the chloroform-soluble fraction of Morus bombycis, using an in vitro PTP1B inhibitory assay led to the identification of three 2-arylbenzofurans, albafuran A (1), mulberrofuran W (2) and mulberrofuran D (6), along with three chalcone-derived Diels-Alder products, kuwanon J (3), kuwanon R (4), and kuwanon V (5).		 35(0,1,1,5) Details