| Name | xanthine oxidase |
|---|---|
| Synonyms | XDH; XDHA; XO; XOD; XOR; Xanthene dehydrogenase; Xanthine dehydrogenase; Xanthine dehydrogenase/oxidase… |
| Name | chloroform |
|---|---|
| CAS | trichloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18515041 | Bouhlel I, Valenti K, Kilani S, Skandrani I, Ben Sghaier M, Mariotte AM, Dijoux-Franca MG, Ghedira K, Hininger-Favier I, Laporte F, Chekir-Ghedira L: Antimutagenic, antigenotoxic and antioxidant activities of Acacia salicina extracts (ASE) and modulation of cell gene expression by H2O2 and ASE treatment. Toxicol In Vitro. 2008 Aug;22(5):1264-72. Epub 2008 Apr 18. TOF and chloroform extracts exhibit antioxidant properties, expressed by the capacity of these extracts to inhibit xanthine oxidase activity. |
81(1,1,1,1) | Details |
| 19467311 | Umamaheswari M, Asokkumar K, Sivashanmugam AT, Remyaraju A, Subhadradevi V, Ravi TK: In vitro xanthine oxidase inhibitory activity of the fractions of Erythrina stricta Roxb. J Ethnopharmacol. 2009 Jul 30;124(3):646-8. Epub 2009 May 23. RESULTS: Among the fractions tested, the chloroform fraction exhibited highest potency (IC (50) 21.2+/-1.6 microg/ml) followed by the pet-ether (IC (50) 30.2+/-2.2 microg/ml), ethyl (IC (50) 44.9+/-1.4 microg/ml) and residual (IC (50) 100+/-3.3 microg/ml) fractions. |
4(0,0,0,4) | Details |
| 18844260 | Boumerfeg S, Baghiani A, Messaoudi D, Khennouf S, Arrar L: Antioxidant properties and xanthine oxidase inhibitory effects of Tamus communis L. root extracts. Phytother Res. 2009 Feb;23(2):283-8. The root extracts chloroform and ethyl and proteins, obtained in distilled water, inhibited bovine, sheep and human milk XO from three species in a concentration-dependent manner, with an additional scavenging capacity, which reached its highest level with ethyl extract (IC (50) = 0.15, 0.04 and 0.09 g/L) for bovine XO, sheep XO and human XO, respectively. |
3(0,0,0,3) | Details |
| 19015021 | Skandrani I, Bouhlel I, Limem I, Boubaker J, Bhouri W, Neffati A, Ben Sghaier M, Kilani S, Ghedira K, Ghedira-Chekir L: Moricandia arvensis extracts protect against DNA damage, mutagenesis in bacteria system and scavenge the Toxicol In Vitro. 2009 Feb;23(1):166-75. Epub 2008 Oct 30. The mutagenic potential of total aqueous, total oligomers flavonoids (TOF), ethyl (EA), chloroform (Chl), petroleum ether (PE) and (MeOH) extracts from aerial parts of Moricandia arvensis was assessed using Ames Salmonella tester strains TA100 and TA1535 with and without metabolic activation (S9), and using plasmid pBluescript DNA assay. Antioxidant capacity of the tested extracts was evaluated using the enzymatic /xanthine oxidase assay) (X/XOD) and the non enzymatic (NBT/ assay) systems. |
2(0,0,0,2) | Details |
| 17663194 | Park JM, Kim SD, Lee WM, Cho JY, Park HJ, Kim TW, Choe NH, Kim SK, Rhee MH: In vitro anti-oxidative and anti-inflammatory effects of solvent-extracted fractions from Suaeda asparagoides. Pharmazie. 2007 Jun;62(6):453-8. All of the solvent fractions showed potent anti-oxidative effects, as assessed using a radical generation assay system (xanthine oxidase assay) and an electron-donating activity system (DPPH [2,2-diphenyl-l-picrylhydrazyl radical] assay), with IC50 values ranging from 9 to 42 microg/ml. All of the solvent fractions significantly suppressed NO production in RAW264.7 cells induced by lipopolysaccharide (LPS, 0.1 microg/ml) and of the fractions, only the chloroform (CHC) fraction completely blocked the expression of inducible NO synthase (iNOS). |
1(0,0,0,1) | Details |
| 17472476 | Lee YS, Chang ZQ, Oh BC, Park SC, Shin SR, Kim NW: Antioxidant activity, anti-inflammatory activity, and whitening effects of extracts of Elaeagnus multiflora Thunb. J Med Food. 2007 Mar;10(1):126-33. Among the solvent extracts of E. multiflora, the ethyl extract (EE) exhibited the highest 1,1-diphenyl-2-picrylhydrazyl radical and xanthine oxidase inhibition activity, as well as the greatest tyrosinase inhibition activity. Only the chloroform extract (CE) inhibited platelet aggregation, and that was a weak effect with 19.29% inhibition at 250 microg/mL, as compared to controls. |
1(0,0,0,1) | Details |
| 20096342 | Khan RA, Khan MR, Sahreen S: Evaluation of Launaea procumbens use in renal disorders: a rat model. J Ethnopharmacol. 2010 Mar 24;128(2):452-61. Epub 2010 Jan 21. Its methanolic, chloroform, ethyl and n-hexane fractions were evaluated against CCl (4)-induced nephrotoxicity in rat. RESULTS: CCl (4) exposure led to a significant oxidative stress in kidneys which was remarkably attenuated with co-administration of various fractions and rutin thereby increased the level of CAT, POD, SOD, GSH, GSR, GST, GSH-Px, quinone reductase, while reduced the xanthine oxidase, gamma-GT, TBARS, H (2) O (2), tissue proteins and DNA fragmentation%. |
1(0,0,0,1) | Details |
| 19538026 | Dellai A, Mansour HB, Limem I, Bouhlel I, Sghaier MB, Boubaker J, Ghedira K, Chekir-Ghedira L: Screening of antimutagenicity via antioxidant activity in different extracts from the flowers of Phlomis crinita Cav. ssp mauritanica munby from the center of Tunisia. Drug Chem Toxicol. 2009;32(3):283-92. Ethyl chloroform, and extracts were prepared from powdered Phlomis flowers and characterized for the presence of tannins, flavonoids, iridoids, sterols, cardiac glycosides, and anthraquinones. All the extracts showed increased activity in scavenging the ABTS free radical, but only ethyl and extracts were active in scavenging the generated by the /xanthine oxidase system. |
1(0,0,0,1) | Details |