Protein Information

Name Myosin
Synonyms Myosin

Compound Information

Name piperazine
CAS piperazine

Reference List

PubMed Abstract RScore(About this table)
16756379 Park D, Xiong YL, Alderton AL, Ooizumi T: Biochemical changes in myofibrillar protein isolates exposed to three oxidizing systems. J Agric Food Chem. 2006 Jun 14;54(12):4445-51.

Myofibrillar protein isolate (MPI) prepared from pork serratus ventralis muscle was suspended (30 mg protein/mL) in 15 mM piperazine-N,N-bis (2-ethane sulfonic acid) buffer (pH 6.0).
The carbonyl content in MOS-treated MPI was the highest, while the TBARS production, changes in thermal properties, and loss of the myosin heavy chain were the greatest in HRGS-treated MPIs.
1(0,0,0,1) Details
12589046 Duran JM, Valderrama F, Castel S, Magdalena J, Tomas M, Hosoya H, Renau-Piqueras J, Malhotra V, Egea G: Myosin motors and not actin comets are mediators of the actin-based Golgi-to-endoplasmic reticulum protein transport. Mol Biol Cell. 2003 Feb;14(2):445-59.

To address this issue we have used, on one hand, a combination of specific inhibitors such as 2,3-butanedione monoxime (BDM) and 1-[5-isoquinoline sulfonyl]-2-methyl piperazine (ML7), which inhibit myosin and the phosphorylation of myosin II by the myosin light chain kinase, respectively; and a mutant of the nonmuscle myosin II regulatory light chain, which cannot be phosphorylated (MRLC2 (AA)).
82(1,1,1,2) Details