| Name | chloride channel (protein family or complex) |
|---|---|
| Synonyms | chloride channel |
| Name | piperazine |
|---|---|
| CAS | piperazine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 13678839 | Harder A, Schmitt-Wrede HP, Krucken J, Marinovski P, Wunderlich F, Willson J, Amliwala K, Holden-Dye L, Walker R: Cyclooctadepsipeptides--an anthelmintically active class of compounds exhibiting a novel mode of action. Int J Antimicrob Agents. 2003 Sep;22(3):318-31. In nematodes, there are five targets for the existing anthelmintics: the nicotinergic acetylcholine receptor which is the target of tetrahydropyrimidines/imidazothiazoles and indirectly that of the acetylcholineesterase inhibitors; the GABA receptor which is the target of piperazine, the -gated chloride channel as the target of the macrocyclic lactones, and beta-tubulin as the target of prebenzimidazoles/benzimidazoles. |
31(0,1,1,1) | Details |
| 19175858 | Chung SD, Kuo YC, Liu SP, Chang HC, Yu HJ, Hsieh JT: The role of channels in rat corpus cavernosum: in vivo study. J Sex Med. 2009 Mar;6(3):708-16. Epub 2008 Oct 29. Injection into the corpus cavernosum of the Cl (-) channel transport inhibitors bumetanide, ethacrynic acid, and HCO (3)-free 4-(2-hydroxyethyl )-1-1- piperazine ethanesulphonic acid buffer, and also increase the ICP. Both crura of the rats were isolated to in order to record intracavernosal pressure (ICP) during basal conditions and electrical stimulation of erection, with and without intracorporeal injection of transport inhibitors, and chloride channel blockers. |
1(0,0,0,1) | Details |