| Name | Cl 2 |
|---|---|
| Synonyms | AMB11; MHC class I NK cell receptor; CD158E1; CD158E1/2; CD158E2; CL 11; CL 2; HLA BW4 specific inhibitory NK cell receptor… |
| Name | piperazine |
|---|---|
| CAS | piperazine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19890942 | Alver O: Complete experimental and theoretical and carbon nuclear magnetic resonance spectral assignments, molecular structure and conformational study of 1-cyclohexylpiperazine and 1-(4-pyridyl) piperazine. Magn Reson Chem. 2010 Jan;48(1):53-60. Solvent effects on nuclear magnetic shielding tensors have been investigated using CDCl (3), CD (3) OD, dimethylsulfoxide (DMSO)-d (6), (CD (3))(2) CO, D (2) O and CD (2) Cl (2). (1) H and (13) C NMR chemical shifts have been calculated for the most stable two conformers, equatorial-equatorial (e-e) and axial-equatorial (a-e) forms of 1-chpp and 1-4pypp using B3LYP/6-311++G (d,p)//6-31G (d) level of theory. |
1(0,0,0,1) | Details |
| 16546259 | Kasuga NC, Onodera K, Nakano S, Hayashi K, Nomiya K: Syntheses, crystal structures and antimicrobial activities of 6-coordinate antimony (III) complexes with tridentate 2-acetylpyridine thiosemicarbazone, bis (thiosemicarbazone) and semicarbazone ligands. J Inorg Biochem. 2006 Jul;100(7):1176-86. Epub 2006 Mar 20. The neutral, 6-coordinate antimony (III) complexes ([Sb (mtsc) Cl (2)] 1, [Sb (mtsc) Br (2)] 2, [Sb (asc) Cl (2)] 3 and [Sb (asc) Br (2)] 4) are depicted with one electron pair (5s (2)) of the antimony (III) atom, deprotonated forms of multidentate thiosemicarbazone or semicarbazone ligands, and two monodentate halogen ligands, respectively. In the dimer complex 5 ([Sb (2)(ptsc) Cl (4)]) with the ligand in which two tridentate thiosemicarbazone moieties are connected by the piperazine moiety, each antimony (III) was also described as a neutral 6-coordinate structure. |
1(0,0,0,1) | Details |
| 16862631 | Feng ML, Prosvirin AV, Mao JG, Dunbar KR: Syntheses, structural studies, and magnetic properties of divalent Cu and Co selenites with organic constituents. Chemistry. 2006 Nov 6;12(32):8312-23. The isostructural compounds [H (2) en][M (HSeO (3))(2) Cl (2)] (en=ethylenediamine; M=Cu (3), Co (4)) contain layers of [MCl (2)(HSeO (3))(2)](2-) units (M=Cu, Co), which are cross-linked by the template cations via bonds into a 3D network. |
1(0,0,0,1) | Details |
| 12968878 | Lemoucheux L, Rouden J, Ibazizene M, Sobrio F, Lasne MC: Debenzylation of tertiary amines using phosgene or triphosgene: an efficient and rapid procedure for the preparation of carbamoyl chlorides and unsymmetrical ureas. J Org Chem. 2003 Sep 19;68(19):7289-97. From [(11) C] phosgene, a common precursor used in the preparation of radiotracers for positron emission tomography, a rapid and efficient synthesis of (11) C-carbamoyl chlorides and (11) C-unsymmetrical ureas derived from tetrahydroisoquinoline and piperazine is described. N-Alkyl-N-benzyl (substituted) tetrahydroisoquinolines, -piperazines, -piperidines, or -anilines were treated with stoichiometric amounts of phosgene (or BTC) in CH (2) Cl (2). |
1(0,0,0,1) | Details |
| 20210078 | Patel NB, Patel SD: Synthesis and in vitro antimicrobial study of Schiff base and thiazolidinone of 1-cyclopropyl-6--7-[4-(2,3-dichlorophenyl) piperazin-1-yl]-4-quinolon e. Acta Pol Pharm. 2010 Jan-Feb;67(1):45-53. The title compounds, 2-substituted phenyl-3-{1-cyclopropyl-6--7-[4-(2,3-dichlorophenylpiperazin-1-yl]-4 -oxo-1,4-dihydroquinoline} carboxamido-1,3-thiazolidin-4-ones 6a-j, have been synthesized after several structural variations viz. hydrazide 2 via acid Schiff base formation and cyclization of Schiff base followed by condensation with N-(2,3-dichlorophenyl) piperazine from the lead molecule 7-chloro-1-cyclopropyl-6--4-oxo-1,4-dihydroquinolin-3-carboxylic acid 1. Compounds 4i, 5i and 6j (2-Cl, 2-Cl and 4-Cl) demonstrated excellent activity compared with ampicillin. |
1(0,0,0,1) | Details |
| 11754267 | Navarro M, Cisneros-Fajardo EJ, Lehmann T, Sanchez-Delgado RA, Atencio R, Silva P, Lira R, Urbina JA: Toward a novel metal-based chemotherapy against tropical diseases. 6. Inorg Chem. 2001 Dec 31;40(27):6879-84. The complexes [Cu (CTZ)(4)] Cl (2).2H (2) O (1), [Cu (CTZ) Cl (2)](2) (2), [Cu (KTZ)(3) Cl (2)] (3), and [Cu (KTZ) Cl (2)](2).2H (2) O (4) were prepared by reaction of CuCl (2) with CTZ and KTZ (where CTZ = 1-[[(2-chlorophenyl) diphenyl] methyl]- and KTZ = cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H--1-ylmethyl)-1,3- dioxolan-4-yl] methoxy] phenyl] piperazine), respectively, in acetonitrile at different ligand to metal molar ratios. |
31(0,1,1,1) | Details |
| 15571863 | Dylag T, Zygmunt M, Maciag D, Handzlik J, Bednarski M, Filipek B, Kiec-Kononowicz K: Synthesis and evaluation of in vivo activity of diphenylhydantoin basic derivatives. Eur J Med Chem. 2004 Dec;39(12):1013-27. Treating this compound as a lead, new derivatives 8-19 were synthesised, differing in piperazine phenyl ring substitution (2-, 3-, 4-Cl, 2-CH3O) as well as in hydantoin N3 alkyl chain (ethyl, ethyl or ethyl 2- |
31(0,1,1,1) | Details |
| 15708793 | Nguewa PA, Fuertes MA, Iborra S, Najajreh Y, Gibson D, Martinez E, Alonso C, Perez JM: soluble cationic trans-platinum complexes which induce programmed cell death in the protozoan parasite Leishmania infantum. J Inorg Biochem. 2005 Mar;99(3):727-36. Epub 2005 Jan 1. We have evaluated the cytotoxic properties against the protozoan Leishmania infantum of four water soluble cationic trans-Pt (II) Cl (2) compounds containing as inert groups NH3 and piperazine (1), 4-picoline and piperazine (2), n-butylamine and piperazine (3), and NH3 and 4-piperidino-piperidine (4). |
6(0,0,1,1) | Details |
| 12431046 | Najajreh Y, Perez JM, Navarro-Ranninger C, Gibson D: Novel soluble cationic trans-diaminedichloroplatinum (II) complexes that are active against cisplatin resistant ovarian cancer cell lines. J Med Chem. 2002 Nov 21;45(24):5189-95. Positively charged, water soluble cis/trans-[PtCl (2)(piperazine)(Am1)] (where Am1 = NH (3), n-butylamine, isopropylamine, 4-picoline, piperidine, and piperazine) has significant cytotoxic activity against cisplatin resistant ovarian cancer cells. Altogether, the results reported here suggest that combination of positively charged ligands with a trans-Pt (II) Cl (2) center may lead to the discovery of platinum complexes that are able to circumvent cisplatin resistance. |
1(0,0,0,1) | Details |
| 20131806 | Yi XY, Lam TC, Williams ID, Leung WH: Hydrolysis of bis (p-nitrophenyl) by tetravalent metal complexes with Klaui's tripodal ligand. Inorg Chem. 2010 Mar 1;49(5):2232-8. At 25 degrees C, with [Ce] = 20 [BNPP], in an -d (6)/N-(2-hydroxyethyl) piperazine-N'-2-ethanesulfonic acid (4:1, v/v) buffer solution (50 mM) (4:1, v/v), the hydrolysis of BNPP with 4 was found to exhibit first-order kinetics with a rate constant of (1.1 +/- 0.1) x 10 (-3) s (-1). The treatment of (NH (4))(2)[Ce (NO (3))(6)] with 2 equiv of NaL (OEt) in water afforded (L (OEt))(2) Ce (NO (3))(2) (3), whereas that with 1 equiv of NaL (OEt) in CH (2) Cl (2) gave L (OEt) Ce (NO (3))(3) (4). |
1(0,0,0,1) | Details |