| Name | myeloperoxidase |
|---|---|
| Synonyms | 38 kDa MYELOPEROXIDASE; MPO; Myeloperoxidase; Myeloperoxidase precursor; Peroxidase (Myeloperoxidase); Myeloperoxidases; Myeloperoxidase precursors; Peroxidase (Myeloperoxidase)s |
| Name | hydrogen cyanide |
|---|---|
| CAS | hydrocyanic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18521543 | Graham GG, Whitehouse MW, Bushell GR: Aurocyanide, dicyano-aurate (I), a pharmacologically active metabolite of medicinal gold complexes. Inflammopharmacology. 2008 Jun;16(3):126-32. Au (CN) (2) (-) is generated from the therapeutic gold complexes by small amounts of hydrogen cyanide, HCN, produced from SCN (-), by myeloperoxidase (MPO) an enzyme in neutrophils which normally produces OCl (-). |
31(0,1,1,1) | Details |
| 36154 | Zgiczynski JM, Stelmaszynska T: Hydrogen cyanide and cyanogen formation by the myeloperoxidase-H2O2-Cl- system. Biochim Biophys Acta. 1979 Apr 12;567(2):309-14. |
12(0,0,1,7) | Details |
| 9744567 | Graham GG, Kettle AJ: The activation of gold complexes by produced by polymorphonuclear leukocytes. Biochem Pharmacol. 1998 Aug 1;56(3):307-12. When the hypothiocyanite decays to hydrogen cyanide, the pro-drug is converted to aurocyanide which then suppresses further oxidant production by these inflammatory cells. The formation of aurocyanide by myeloperoxidase.. |
4(0,0,0,4) | Details |
| 2989021 | Stelmaszynska T: Formation of HCN by human phagocytosing neutrophils--1. Int J Biochem. 1985;17(3):373-9. One of the substrates yielding HCN during phagocytosis are N-dichloroglycyl residues of bacterial peptidoglycan formed by the chlorinating myeloperoxidase-H2O2-Cl- system of neutrophils. |
1(0,0,0,1) | Details |
| 14642392 | Klein I, Nagler RM, Toffler R, van Der Vliet A, Reznick AZ: Effect of cigarette smoke on oral peroxidase activity in human saliva: role of hydrogen cyanide. Free Radic Biol Med. 2003 Dec 1;35(11):1448-52. Peroxidase activity in human saliva is composed of salivary peroxidase (80%), of salivary glandular origin, and myeloperoxidase (20%), of leukocyte origin. |
1(0,0,0,1) | Details |
| 215410 | Stelmaszynska T, Zgliczynski JM: N-(2-Oxoacyl) amino acids and nitriles as final products of dipeptide chlorination mediated by the myeloperoxidase/H2O2/Cl- system. Eur J Biochem. 1978 Dec 1;92(1):301-8. N-Dichloroglycyl-amino acid decomposes through a relatively stable intermediate (cyano-formylamino acid) to hydrogen cyanide, cyanogen and the free C-terminal amino acid. |
1(0,0,0,1) | Details |