| Name | superoxide dismutase |
|---|---|
| Synonyms | IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD… |
| Name | anthraquinone |
|---|---|
| CAS | 9,10-anthracenedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20219682 | Liu B, Xie J, Ge X, Xu P, Wang A, He Y, Zhou Q, Pan L, Chen R: Effects of anthraquinone extract from Rheum officinale Bail on the growth performance and physiological responses of Macrobrachium rosenbergii under high temperature stress. Fish Shellfish Immunol. 2010 Feb 26. After high temperature stress, 0.1-0.2% anthraquinone extract also could improve the haemolymph total proteins, lysozyme and ALP activities, hepatic catalase, and superoxide dismutase, and reduce haemolymph ALT and AST activities, hepatic malondialdehyde contents. |
32(0,1,1,2) | Details |
| 7618176 | Leskovac V, Trivic S, Peggins JO: Primary toxic effects of anthraquinone-2- in rat liver microsomes. Toxicol Lett. 1995 Jul;78(2):107-10. (1) The endogenous, -supported production of H2O2 and of O2-.-radicals in rat liver microsomes was very strongly enhanced in the presence of anthraquinone-2- (AQSA). (2) This induction of H2O2 and of O2-.-radicals was catalyzed by the microsomal NADPH:cytochrome P450 oxidoreductase (EC 1.6.2.4). (3) AQSA was reduced to AQSA radicals by reductase; AQSA radicals reduce molecular to O2-.-radicals, which are readily dismutated to H2O2 by the microsomal superoxide dismutase. (4) O2-.-radicals are the sole precursors of all AQSA-induced production of H2O2 in liver microsomes. |
31(0,1,1,1) | Details |
| 16662512 | Vernon LP, Cardon S: Direct Spectrophotometric Measurement of Photosystem I and Photosystem II Activities of Photosynthetic Membrane Preparations from Cyanophora paradoxa, Phormidium laminosum, and Spinach. Plant Physiol. 1982 Aug;70(2):442-445. Anthraquinone-2-sulfonate was the better electron acceptor, and maximal rates of 943 micromoles per hour per milligram chlorophyll for O (2) uptake were observed for Phormidium laminosum preparations in the presence of superoxide dismutase. |
6(0,0,1,1) | Details |
| 223343 | Lengfelder E, Elstner EF: insensitive iron superoxide dismutase in Euglena gracilis. Z Naturforsch C. 1979 May-Jun;34C(5-6):374-80. If O2.- is generated chemically (autoxidation of reduced anthraquinone), photochemically (illuminated or pulse radiolytically, only protein P1 but not P2 shows SOD activity. |
6(0,0,0,6) | Details |
| 3094197 | Wallace KB: Nonenzymatic activation and stimulation of lipid peroxidation by doxorubicin- Toxicol Appl Pharmacol. 1986 Oct;86(1):69-79. Associated with these changes was a -dependent consumption of dissolved and a superoxide dismutase-sensitive reduction of ferricytochrome c, suggesting the liberation of free radicals. The suggested occurrence of doxorubicin- complexes in vivo infers that nonenzymatic generation of -free radicals by the chelate may contribute to the mechanism of toxicity of doxorubicin and related anthraquinone anticancer agents observed clinically. |
2(0,0,0,2) | Details |
| 18590720 | Ding Y, Zhao L, Mei H, Zhang SL, Huang ZH, Duan YY, Ye P: Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway. Eur J Pharmacol. 2008 Aug 20;590(1-3):377-86. Epub 2008 Jun 17. Emodin, 1,3,8-trihydroxy-6-methyl-anthraquinone, is an anthraquinone derivative from the roots of Rheum officinale Baill that has been used to treat many diseases in digestive system for thousands of years. At 24 h, 48 h and 72 h time points after administration, liver function, pathological changes of hepatic tissue, tumor necrosis factor (TNF)-alpha, interleukin (IL)-6, myeloperoxidase (MPO), malondialdehyde (MDA), superoxide dismutase (SOD), cytokine-induced neutrophil chemoattractant (CINC)-1, macrophage inflammatory protein (MIP)-2, intercellular adhesion molecule (ICAM)-1, nuclear factor (NF)-kappaB and early growth response (Egr)-1, (NO) and inducible synthase (iNOS) were detected. |
1(0,0,0,1) | Details |
| 1535596 | Huang HC, Chang JH, Tung SF, Wu RT, Foegh ML, Chu SH: Immunosuppressive effect of emodin, a free radical generator. Eur J Pharmacol. 1992 Feb 18;211(3):359-64. The structure-activity relationship of emodin and 10 other anthraquione derivatives indicates that the free group at the beta-position of the anthraquinone nucleus plays an important role in the immunosuppressive effect. The suppressive activity of emodin was significantly inhibited by catalase (a scavenger of peroxide), but little affected by superoxide dismutase (a scavenger of and (a scavenger of |
1(0,0,0,1) | Details |
| 2753390 | Monteiro HP, Vile GF, Winterbourn CC: Release of iron from ferritin by semiquinone, anthracycline, bipyridyl, and nitroaromatic radicals. Free Radic Biol Med. 1989;6(6):587-91. Ferritin iron was released by a number of bipyridyl radicals including those derived from diquat and paraquat, the anthracycline radicals of adriamycin, daunorubicin and epirubicin, the semiquinones of anthraquinone-2-sulphonate, 1,5 and 2,6-dihydroxyanthraquinone, 1-hydroxyanthraquinone, purpurin, and plumbagin, and the nitroaromatic radicals of nitrofurantoin and metronidazole. In air, iron release was inhibited by superoxide dismutase. |
2(0,0,0,2) | Details |
| 17444804 | Lin HJ, Lai CC, Lee Chao PD, Fan SS, Tsai Y, Huang SY, Wan L, Tsai FJ: Aloe-emodin metabolites protected -treated retinal ganglion cells by Cu-Zn superoxide dismutase. J Ocul Pharmacol Ther. 2007 Apr;23(2):152-71. Our previous study had found that aloe-emodin sulfates/glucuronides metabolites, an anthraquinone polyphenol, exerted a neuroprotective activity upon RGCs. |
2(0,0,0,2) | Details |
| 9888634 | Mori S, Kawai K, Nozawa Y, Ogihara Y: The redox reaction and biotransformation of rubroskyrin, a modified bis-anthraquione from Penicillium islandicum Sopp. Nat Toxins. 1998;6(2):85-90. Rubroskyrin, a modified bis-anthraquinone pigment from Penicillium islandicum Sopp, was studied on the redox interaction with -linked redox system of rat liver microsomes, comparing with luteoskyrin and rugulosin. The H2O2 production was significantly accelerated by superoxide dismutase (SOD), suggesting the production of during the reduction-autoxidation cycles of rubroskyrin. |
1(0,0,0,1) | Details |
| 17427930 | Garcia-Gil De Munoz F, Lanz-Mendoza H, Hernandez-Hernandez FC: Free radical generation during the activation of hemolymph prepared from the homopteran Dactylopius coccus. Arch Insect Biochem Physiol. 2007 May;65(1):20-8. This reduction was prevented by superoxide dismutase (SOD) indicating O (-) (2) generation. The probable source of O (-) (2) in the D. coccus hemolymph is the anthraquinone oxidation, since commercial carminic dye produced O (-) (2) during its oxidation by Agaricus bisporus tyrosinase. |
1(0,0,0,1) | Details |
| 17197137 | Xia Q, Yin JJ, Fu PP, Boudreau MD: Photo-irradiation of Aloe vera by UVA--formation of free radicals, singlet and induction of lipid peroxidation. Toxicol Lett. 2007 Jan 30;168(2):165-75. Epub 2006 Dec 6. This paper examines the photochemical properties of two Aloe vera whole leaf extracts that differed in their anthraquinone content. Superoxide dismutase and azide inhibited and deuterium oxide enhanced the formation of lipid peroxides, suggesting that singlet and were involved in the mechanism. |
1(0,0,0,1) | Details |
| 1667913 | Huang HC, Lee CR, Chao PD, Chen CC, Chu SH: Vasorelaxant effect of emodin, an anthraquinone from a Chinese herb. Eur J Pharmacol. 1991 Dec 3;205(3):289-94. The relaxation response to emodin was inhibited by free radical scavengers, superoxide dismutase, catalase and and guanylate cyclase inhibitors, methylene blue and hemoglobin. |
1(0,0,0,1) | Details |
| 19066858 | Kishikawa N, Ohkubo N, Ohyama K, Nakashima K, Kuroda N: Chemiluminescence assay for quinones based on generation of reactive species through the redox cycle of Anal Bioanal Chem. 2009 Feb;393(4):1337-43. Epub 2008 Dec 6. It is concluded that was involved in the proposed chemiluminescence reaction because the chemiluminescence intensity was decreased only in the presence of superoxide dismutase. Among the tested quinones, the chemiluminescence was observed from 9,10-phenanthrenequinone, 1,2-naphthoquinone, and 1,4-naphthoquinone, whereas it was not observed from 9,10-anthraquinone and |
1(0,0,0,1) | Details |
| 17552159 | Liu JZ, Lin X, Li XE, Guo BJ: [Effect of protein and anthraquinone glucosides from Semen Cassia on learning and memory capacity and related substances of senile mice induced by Zhongguo Zhong Yao Za Zhi. 2007 Mar;32(6):516-9. |
0(0,0,0,0) | Details |
| 8646615 | Winston GW, Moore MN, Kirchin MA, Soverchia C: Production of reactive species by hemocytes from the marine mussel, Mytilus edulis: lysosomal localization and effect of xenobiotics. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1996 Feb;113(2):221-9. Uptake of the anthraquinone, purpurin, and FeEDTA with DHR greatly amplified fluorescence within the lysosomes. |
0(0,0,0,0) | Details |