| Name | NR1 |
|---|---|
| Synonyms | GRIN 1; NR1; GRIN1; Glutamate [NMDA] receptor subunit zeta 1; Glutamate [NMDA] receptor subunit zeta 1 precursor; N methyl D aspartate receptor subunit NR1; NMDA receptor 1; NMDA 1… |
| Name | anthraquinone |
|---|---|
| CAS | 9,10-anthracenedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17404801 | Kashiwagi K, Williams K, Igarashi K: Anthraquinone polyamines: novel channel blockers of N-methyl-D-aspartate receptors. Amino Acids. 2007 Aug;33(2):299-304. Epub 2007 Apr 4. Results using mutant NR1 and NR2 subunits identified amino acid residues that influence blockade by anthraquinone polyamines. |
31(0,1,1,1) | Details |
| 17050777 | Jin L, Sugiyama H, Takigawa M, Katagiri D, Tomitori H, Nishimura K, Kaur N, Phanstiel O 4th, Kitajima M, Takayama H, Okawara T, Williams K, Kashiwagi K, Igarashi K: Comparative studies of anthraquinone- and anthracene-tetraamines as blockers of N-methyl-D-aspartate receptors. J Pharmacol Exp Ther. 2007 Jan;320(1):47-55. Epub 2006 Oct 18. Results of experiments using mutant NR1 and NR2B subunits of NMDA receptor identified residues that influence block by AQ- and Ant-tetraamines. |
2(0,0,0,2) | Details |
| 14764657 | Kashiwagi K, Tanaka I, Tamura M, Sugiyama H, Okawara T, Otsuka M, Sabado TN, Williams K, Igarashi K: Anthraquinone polyamines: novel channel blockers to study N-methyl-D-aspartate receptors. J Pharmacol Exp Ther. 2004 Jun;309(3):884-93. Epub 2004 Feb 5. All AQP derivatives inhibited responses of NR1/NR2 receptors in oocytes voltage-clamped at -70 mV, with IC (50) values between 4 and 22 microM. |
2(0,0,0,2) | Details |