Protein Information

Name aquaporin 2
Synonyms ADH water channel; AQP 2; AQP CD; AQP2; Aquaporin 2; Aquaporin CD; Collecting duct water channel protein; WCH CD…

Compound Information

Name anthraquinone
CAS 9,10-anthracenedione

Reference List

PubMed Abstract RScore(About this table)
18841780 Bao JQ, Li F, Zhang WS, Xu YB, Liu Q, Wang X, Zhao YL, Wang CH: [Effect of total anthraquinone in rheum on aquaporin 2 expression in rat distal colon]. Zhongguo Zhong Yao Za Zhi. 2008 Jul;33(14):1732-5.

CONCLUSION: Total anthraquinone in rheum can reduce the transcription and translation of AQP2 in rats' distal colon, increase fecal water content, which probably is one of the mechanisms of diarrhea caused by total anthraquinone in rheum.
95(1,1,3,5) Details
19317169 Bao JQ, Li F, Zhang WS: [Effect of rhubarb on expressions of aquaporin-2 and -4 in rat's kidney] . Zhongguo Zhong Xi Yi Jie He Za Zhi. 2008 Dec;28(12):1108-11.

METHODS: Thirty-two SD rats were randomly divided into 4 groups, the normal control group, and the three rhubarb groups medicated via gastrogavage with low, mid and high dose of rhubarb extract (total anthraquinone) respectively.
5(0,0,0,5) Details