| Name | kynurenine formamidase |
|---|---|
| Synonyms | AFMID; Arylformamidase; KF; Kynurenine formamidase; Probable arylformamidase; Arylformamidases; Kynurenine formamidases; Probable arylformamidases |
| Name | diazinon |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1282004 | Seifert J, Pewnim T: Alteration of mice metabolism by the organophosphorous acid triester diazinon. Biochem Pharmacol. 1992 Dec 1;44(11):2243-50. Liver kynurenine formamidase was inhibited almost completely by diazinon (10 mg/kg). |
81(1,1,1,1) | Details |
| 8314934 | Seifert J: Assay of tryptophan 2,3-dioxygenase using liver slices and high-performance liquid chromatography. J Chromatogr. 1993 May 5;614(2):227-31. Kynurenine formamidase inhibition by diazinon resulted in reduced KYN formation, FK accumulation, and moderate TDO increase. |
81(1,1,1,1) | Details |
| 6186043 | Henderson M, Kitos PA: Do organophosphate insecticides inhibit the conversion of to NAD+ in ovo?. Teratology. 1982 Oct;26(2):173-81. The hypothesis that organophosphate (OP) insecticides reduce the NAD+ levels of chick embryos by inhibiting kynurenine formamidase was tested. Fertile chicken eggs at 3 days of incubation were treated with a teratogenic dose of the organophosphate insecticide diazinon (DZN) in the presence or absence of exogenous or or one of the metabolic intermediates (L-kynurenine, 3-hydroxyanthranilic acid, quinolinic acid) between tryptophan and NAD+. |
1(0,0,0,1) | Details |
| 7507440 | Pewnim T, Seifert J: Structural requirements for altering the metabolism in mice by organophosphorous and methylcarbamate insecticides. Eur J Pharmacol. 1993 Oct 1;248(3):237-41. Replacement of by in the phosphorothioate diazinon reduced in vivo liver kynurenine formamidase inhibition. |
85(1,1,1,5) | Details |
| 6156523 | Eto M, Seifert J, Engel JL, Casida JE: Organophosphorus and methylcarbamate teratogens: structural requirements for inducing embryonic abnormalities in chickens and kynurenine formamidase inhibition in mouse liver. Toxicol Appl Pharmacol. 1980 Jun 15;54(1):20-30. |
1(0,0,0,1) | Details |