Protein Information

Name aquaporin 4
Synonyms AQP 4; AQP4; Aquaporin 4; HMIWC 2; HMIWC2; MIWC; Mercurial insensitive water channel; WCH 4…

Compound Information

Name anthraquinone
CAS 9,10-anthracenedione

Reference List

PubMed Abstract RScore(About this table)
20353011 Liu Q, Li F, Li J, Yao J, Wang X, Wang C, Wang W: [Regulating effects of aquaporin 4 expression in LoVo cells by serum containing total anthraquinone in rheum]. Zhongguo Zhong Yao Za Zhi. 2009 Dec;34(24):3247-50.

CONCLUSION: Serum containing total anthraquinone in rheum can inhibit both the transcription and translation of AQP4 gene, indicating that the regulation mechanism of rhubarb on the expression of AQP4 can be related to the cathartic effect of rhubarb.
94(1,1,3,4) Details
19065897 Zhang WS, Li F, Bao JQ: [Regulatory effect of anthraquinone derivatives from rhubarb on aquaporin 4 expression in colon of rats and in LoVo cell line]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2008 Sep;28(9):818-23.
93(1,1,2,8) Details
19317169 Bao JQ, Li F, Zhang WS: [Effect of rhubarb on expressions of aquaporin-2 and -4 in rat's kidney] . Zhongguo Zhong Xi Yi Jie He Za Zhi. 2008 Dec;28(12):1108-11.

OBJECTIVE: To investigate the effect of rhubarb on expressions of aquaporin-2 and 4 (AQP2 and AQP4) in rat's kidney.
METHODS: Thirty-two SD rats were randomly divided into 4 groups, the normal control group, and the three rhubarb groups medicated via gastrogavage with low, mid and high dose of rhubarb extract (total anthraquinone) respectively.
4(0,0,0,4) Details