Protein Information

Name Prolidase
Synonyms Imidodipeptidase; PEPD; PRD; PROLIDASE; Peptidase D; Proline dipeptidase; X Pro dipeptidase; Xaa Pro dipeptidase…

Compound Information

Name anthraquinone
CAS 9,10-anthracenedione

Reference List

PubMed Abstract RScore(About this table)
9972056 Bielawska A, Bielawski K, Palka J: Prolidase as a prodrug converting enzyme. Rocz Akad Med Bialymst. 1998;43:201-9.

The synthesis of proline analogue of anthraquinone-2-carboxylic acid (potential antineoplastic agent) conjugated through imido-bond (potential target for prolidase action) has been performed.
227(2,4,4,7) Details
11820611 Bielawska A, Bielawski K, Palka J: Cytotoxicity activity of L-proline analogues of anthraquinone-2-carboxylic acid in breast cancer MCF-7 cells. Folia Histochem Cytobiol. 2001;39 Suppl 2:207-8.

Although prolidase [E.C.3.4.13.9] is found in normal cells, substantially increased levels are found in some neoplastic tissues.
3(0,0,0,3) Details