| Name | alkaline phosphatase |
|---|---|
| Synonyms | ALP 1; Alkaline phosphatase; ALPG; ALPPL; ALPPL 2; ALPPL2; GCAP; Germ cell alkaline phosphatase… |
| Name | anthraquinone |
|---|---|
| CAS | 9,10-anthracenedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8950490 | Yamana K, Mitsui T, Yoshioka J, Isuno T, Nakano H: Incorporation of two anthraquinonylmethyl groups into the 2'-O-positions of oligonucleotides: increased affinity and sequence specificity of anthraquinone-modified oligonucleotides in hybrid formation with DNA and RNA. Bioconjug Chem. 1996 Nov-Dec;7(6):715-20. The base compositions and the presence of anthraquinone group (s) in the oligonucleotides were verified with enzymatic digestion (snake venom phosphodiesterase and alkaline phosphatase) analysis and UV-vis spectral measurements. |
6(0,0,1,1) | Details |
| 2753945 | Lindner NM, Jeffcoat R, Lowe CR: Design and applications of biomimetic anthraquinone dyes. J Chromatogr. 1989 Jun 28;473(1):227-40. A 330-fold one-step purification of alkaline phosphatase from a crude calf intestinal extract has been achieved using specific elution with inorganic (5 mM) from a purpose designed adsorbent comprising a terminal ring phosphonate analogue of C.I. |
2(0,0,0,2) | Details |
| 3446194 | Kirchberger J, Seidel H, Kopperschlager G: Interaction of procion red HE-3B and other reactive dyes with alkaline phosphatase: a study by means of kinetic, difference spectroscopic and chromatographic methods. Biomed Biochim Acta. 1987;46(10):653-63. Large aromatic parts of a dye molecule like a combination of two naphthol ring systems or an anthraquinone ring flanked by spatially arranged charged substituents are important for the extent of specificity. |
2(0,0,0,2) | Details |
| 19800773 | Bhadauria M: Dose-dependent hepatoprotective effect of emodin against -induced acute damage in rats. Exp Toxicol Pathol. 2009 Oct 2. Protective effect of emodin (1,3,8-trihydroxy-6-methyl anthraquinone), an active compound of Ventilago madraspatana Gaertn., was evaluated against -induced biochemical and histological alterations in rats. (2g/kg, po) administration caused significant elevation in the release of serum transaminases, alkaline phosphatase, lactate dehydrogenase, serum and serum protein with concomitant decrease in hemoglobin and blood sugar after 24h of its administration. |
2(0,0,0,2) | Details |
| 17257888 | Xiao B, Guo J, Liu D, Zhang S: Aloe-emodin induces in vitro G2/M arrest and alkaline phosphatase activation in human oral cancer KB cells. Oral Oncol. 2007 Oct;43(9):905-10. Epub 2007 Jan 25. Aloe-emodin is a natural anthraquinone compound from the root and rhizome of Rheum palmatum. |
2(0,0,0,2) | Details |
| 18590720 | Ding Y, Zhao L, Mei H, Zhang SL, Huang ZH, Duan YY, Ye P: Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway. Eur J Pharmacol. 2008 Aug 20;590(1-3):377-86. Epub 2008 Jun 17. Emodin, 1,3,8-trihydroxy-6-methyl-anthraquinone, is an anthraquinone derivative from the roots of Rheum officinale Baill that has been used to treat many diseases in digestive system for thousands of years. As a result, compared to the controls, Emodin had a notable effect on rat's living condition, pathological manifestation of hepatic tissue, total direct alanine aminotransferase (ALT) and aspartate aminotransferase (AST) (P <0.05), but had little effect on alkaline phosphatase (ALP), gamma-glutamyltransferase (GGT) and total bile acid. |
1(0,0,0,1) | Details |
| 12852760 | Huang HS, Chiou JF, Fong Y, Hou CC, Lu YC, Wang JY, Shih JW, Pan YR, Lin JJ: Activation of human telomerase reverse transcriptase expression by some new symmetrical bis-substituted derivatives of the anthraquinone. J Med Chem. 2003 Jul 17;46(15):3300-7. To facilitate the analysis of the expression of telomerase, we used cancer and normal cell lines that carry secreted alkaline phosphatase (SEAP) gene under the control of human telomerase reverse transcriptase (hTERT). |
1(0,0,0,1) | Details |
| 18387517 | Lee SU, Shin HK, Min YK, Kim SH: Emodin accelerates osteoblast differentiation through phosphatidylinositol 3-kinase activation and bone morphogenetic protein-2 gene expression. Int Immunopharmacol. 2008 May;8(5):741-7. Epub 2008 Feb 22. Emodin is a naturally occurring anthraquinone present in the roots and bark of numerous plants of the genus Rhamnus. Without any effect on cell growth, the low concentration (up to 5 microM) of emodin highly induced the mRNA expression of BMP-2, the expression of alkaline phosphatase (an early marker of osteoblast differentiation), and the mineralization. |
1(0,0,0,1) | Details |
| 19067753 | Bhadauria M, Nirala SK, Shrivastava S, Sharma A, Johri S, Chandan BK, Singh B, Saxena AK, Shukla S: Emodin reverses CCl induced hepatic cytochrome P450 (CYP) enzymatic and ultrastructural changes: The in vivo evidence. Hepatol Res. 2009 Mar;39(3):290-300. Epub 2008 Dec 2. Aim: The curative effect of emodin (1,3,8-trihydroxy-6-methyl anthraquinone), an active compound of the plant species Ventilago maderaspatana Gaertn, was evaluated against carbon tetrachloride (CCl (4)) induced hepatic cytochrome P450 (CYP) enzymatic and ultrastructural alterations in rats. Results: The CCl (4) induced-toxic effects were observed with sharp elevation in the release of serum transaminases, alkaline phosphatase, lactate dehydrogenase and gamma-glutamyl transpeptidase. |
1(0,0,0,1) | Details |
| 20219682 | Liu B, Xie J, Ge X, Xu P, Wang A, He Y, Zhou Q, Pan L, Chen R: Effects of anthraquinone extract from Rheum officinale Bail on the growth performance and physiological responses of Macrobrachium rosenbergii under high temperature stress. Fish Shellfish Immunol. 2010 Feb 26. The growth, changes in haemolymph total protein, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lysozyme, (NO) and hepatic catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA) were investigated. |
1(0,0,0,1) | Details |
| 19061946 | He ZH, He MF, Ma SC, But PP: Anti-angiogenic effects of rhubarb and its anthraquinone derivatives. . J Ethnopharmacol. 2009 Jan 21;121(2):313-7. Epub 2008 Nov 17. MATERIALS AND METHODS: The 95% extract and four subsequent fractions (n-hexane, ethyl and aqueous fractions) of rhubarb root and five anthraquinone derivatives were investigated on zebrafish model by quantitative endogenous alkaline phosphatase assay and staining assay. |
81(1,1,1,1) | Details |