| Name | beta hexosaminidase |
|---|---|
| Synonyms | Beta N acetylhexosaminidase; Beta hexosaminidase A; Beta hexosaminidase alpha chain; Beta hexosaminidase alpha chain precursor; HEXA; HEXA protein; Hexosaminidase A; Hexosaminidase A preproprotein variant… |
| Name | anthraquinone |
|---|---|
| CAS | 9,10-anthracenedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12808242 | Tao J, Morikawa T, Ando S, Matsuda H, Yoshikawa M: Bioactive constituents from Chinese natural medicines. Chem Pharm Bull. 2003 Jun;51(6):654-62. In addition, an anthraquinone constituent, 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone, was found to show inhibitory effects on the release of beta-hexosaminidase in RBL-2H3 cells. |
81(1,1,1,1) | Details |
| 16814590 | Theodossiou TA, Noronha-Dutra A, Hothersall JS: Mitochondria are a primary target of hypericin phototoxicity: synergy of intracellular mobilisation in cell killing. Int J Biochem Cell Biol. 2006;38(11):1946-56. Epub 2006 May 27. Hypericin, a naturally occurring anthraquinone synthesised by hypericum, upon light activation exhibits photodynamic cytotoxicity attributed mainly to the production of reactive species. Evaluation of the lysosomal enzyme hexosaminidase activity showed: (a) 60% cell loss 22 h following irradiation (1.5 J cm (-2)) and (b) a steady rate of lysosomal leakage to the cytosol (25%), at the same time and irradiation. |
1(0,0,0,1) | Details |