| Name | protein tyrosine kinase |
|---|---|
| Synonyms | Acidic fibroblast growth factor; Tyrosylprotein kinase; Protein tyrosine kinase; Hydroxyaryl protein kinase; CD334; CD334 antigen; FGF receptor 4; FGFR 4… |
| Name | anthraquinone |
|---|---|
| CAS | 9,10-anthracenedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1517743 | Jayasuriya H, Koonchanok NM, Geahlen RL, McLaughlin JL, Chang CJ: Emodin, a protein tyrosine kinase inhibitor from Polygonum cuspidatum. J Nat Prod. 1992 May;55(5):696-8. Bioassay-directed fractionation of a Chinese medicinal plant, Polygonum cuspidatum (Polygonaceae), has led to the discovery of an anthraquinone, emodin [1], as a strong inhibitor of a protein tyrosine kinase (p56lck) partially purified from bovine thymus. |
83(1,1,1,3) | Details |
| 8744799 | Chang CJ, Ashendel CL, Geahlen RL, McLaughlin JL, Waters DJ: Oncogene signal transduction inhibitors from medicinal plants. In Vivo. 1996 Mar-Apr;10(2):185-90. Protein-tyrosine kinase-directed fractionation and separation of the crude extracts of Polygonum cuspidatum and Koelreuteria henryi have led to the isolation of three different classes of protein-tyrosine kinase inhibitors, anthraquinone, stilbene and |
31(0,1,1,1) | Details |
| 17019678 | Srinivas G, Babykutty S, Sathiadevan PP, Srinivas P: Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent. Med Res Rev. 2007 Sep;27(5):591-608. Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a naturally occurring anthraquinone present in the roots and barks of numerous plants, molds, and lichens, and an active ingredient of various Chinese herbs. Emodin, first assigned to be a specific inhibitor of the protein tyrosine kinase p65lck, has now a number of cellular targets interacting with it. |
1(0,0,0,1) | Details |