Protein Information

Name glial cell line derived neurotrophic factor
Synonyms ATF 1; Atf1; ATF2; ATF 2; Astrocyte derived trophic factor 1; GDNF; Glial cell derived neurotrophic factor; Glial cell line derived neurotrophic factor…

Compound Information

Name diazinon
CAS

Reference List

PubMed Abstract RScore(About this table)
19596371 Harris W, Sachana M, Flaskos J, Hargreaves AJ: Neuroprotection from diazinon-induced toxicity in differentiating murine N2a neuroblastoma cells. Neurotoxicology. 2009 Nov;30(6):958-64. Epub 2009 Jul 9.

In conclusion, these data demonstrate that C6 conditioned medium protects N2a cells from the neurite inhibitory effects of diazinon by blocking molecular events leading to axon damage and that GDNF is implicated in these effects.
112(1,2,2,2) Details