| Name | dopamine beta hydroxylase |
|---|---|
| Synonyms | DBH; DBM; Dopamine beta hydroxylase; Dopamine beta monooxygenase; Dopamine beta hydroxylase precursor; dopamine beta hydroxylase (dopamine beta monooxygenase); DBH; Dopamine beta hydroxylases… |
| Name | thiram |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8318751 | Stoker TE, Goldman JM, Cooper RL: The dithiocarbamate fungicide thiram disrupts the hormonal control of ovulation in the female rat. Reprod Toxicol. 1993 May-Jun;7(3):211-8. Thiram has been reported to inhibit dopamine-beta-hydroxylase (D beta H), thereby affecting (NE) synthesis. |
81(1,1,1,1) | Details |
| 6420938 | Serio R, Long RA, Taylor JE, Tolman RL, Weppelman RM, Olson G: The antifertility and antiadrenergic actions of thiocarbamate fungicides in laying hens. Toxicol Appl Pharmacol. 1984 Feb;72(2):333-42. Inhibition experiments with dopamine beta-hydroxylase purified from chicken adrenals indicated that thiram, ziram, and ferbam are potent competitive inhibitors with the substrate the substrate |
62(0,2,2,2) | Details |
| 8572926 | Caroldi S, De Paris P: Comparative effects of two dithiocarbamates disulfiram and thiram, on catecholamine content and on plasma dopamine-beta-hydroxylase activity. Arch Toxicol. 1995;69(10):690-3. |
7(0,0,1,2) | Details |
| 3006637 | Komulainen H, Savolainen K: Effect of dithiocarbamate fungicides and thiurams on 3H-haloperidol binding in rat brain. Arch Toxicol Suppl. 1985;8:77-9. As one biochemical indicator of the toxicity, dopamine-beta-hydroxylase is inhibited in the brain. It appeared that ferbam, maneb, nabam, zineb, disulfiram, thiram and ethylene thiourea did not change significantly D2-receptor binding at doses which were already overtly toxic. |
1(0,0,0,1) | Details |
| 5548772 | Lippmann W, Lloyd K: Effects of tetramethylthiuram disulfide and structurally-related compounds on the dopamine-beta-hydroxylase activity in the rat and hamster. Arch Int Pharmacodyn Ther. 1971 Feb;189(2):348-57. |
1(0,0,0,1) | Details |