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thiram

Identification (Source:EPA,EU)

ID	368
Name	thiram
CAS	137-26-8
IUPAC
Inchi	InChI=1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3
CIPAC	24
EPA Code	079801
Formula	C6H12N2S4
SMILES	S=C(SSC(=S)N(C)C)N(C)C
Status	Approved

Classification

Mode of Action	Contact action with protective properties, acts by inhibiting spore germination and mycelial growth. Repellent properties caused by aversion to its taste.
Pesticide Type	Fungicide, Repellent, Metabolite
Chemical Group	Dithiocarbamate
Classification	dithiocarbamate fungicides Bird repellents

Properties (Source:PubChem)

Molecular Weight	240.43
Physical State	White to yellow crystalline powder
AlogP	4.204
H-Bond Donor	0
H-Bond Acceptor	4
Surface Area	251.82
Polar Surface Area	121.26

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.065 mg l-1
Aquatic crustaceans	Acute	96 hour	LC50	0.0033 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.011 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.008 mg l-1
Aquatic plants	Acute	7 day	EC50, biomass	1.6 mg l-1
Birds	Acute		LD50	> 2000 mg kg-1
Birds	Short term dietary		LC50/LD50	> 947 mg/kg bw/day
Earthworms	Acute	14 day	LD50	540 mg kg-1
Fish	Chronic	21 day	NOEC	0.012 mg l-1
Fish	Acute	96 hour	LC50	0.046 mg l-1
Honeybees	Acute	48 hour	LD50	> 100 μg bee-1
Mammals	Acute oral		LD50	> 1800 mg kg-1
Mammals	Short term dietary		NOEL	1.5 mg kg-1
	Bio-concentration factor		BCF	6
	Bio-concentration factor		CT50	Not available days

Related targets

Target Name	RScore (About this table)
CS2	359(3,6,8,19)	Details
11 beta hydroxysteroid dehydrogenase type 2	315(3,5,6,10)	Details
cytochrome P450 (protein family or complex)	243(2,4,6,13)	Details
glutathione reductase	241(2,4,6,11)	Details
superoxide dismutase	183(2,2,5,8)	Details
glucocorticoid receptor	169(2,2,3,4)	Details
dopamine beta hydroxylase	152(1,3,4,7)	Details
vascular endothelial growth factor	124(1,2,4,4)	Details
bcl 2	112(1,2,2,2)	Details
demethylase	88(1,1,2,3)	Details
C18	87(1,1,2,2)	Details
alkaline phosphatase	85(1,1,1,5)	Details
lactate dehydrogenase (protein family or complex)	83(1,1,1,3)	Details
acid phosphatase	82(1,1,1,2)	Details
caspases (protein family or complex)	82(1,1,1,2)	Details
CD1	81(1,1,1,1)	Details
CYP2E1	81(1,1,1,1)	Details
Microsomal monooxygenase	81(1,1,1,1)	Details
VEGFR1	81(1,1,1,1)	Details
K12	81(1,1,1,1)	Details
aldehyde oxidase	81(1,1,1,1)	Details
lipoprotein lipase	43(0,1,3,3)	Details
transferase	39(0,1,2,4)	Details
glutathione S transferase	35(0,1,1,5)	Details
VEGFR2	31(0,1,1,1)	Details
chitinase	31(0,1,1,1)	Details
staring	31(0,1,1,1)	Details
histone deacetylase (protein family or complex)	31(0,1,1,1)	Details

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