Protein Information

Name bcl 2
Synonyms Apoptosis regulator Bcl 2; B cell CLL/lymphoma 2; B cell lymphoma protein 2 alpha; B cell lymphoma protein 2 alpha isoform; BCL2; Bcl 2; B cell CLL/lymphoma 2s; B cell lymphoma protein 2 alphas…

Compound Information

Name thiram
CAS

Reference List

PubMed Abstract RScore(About this table)
17954590 Rath NC, Huff WE, Huff GR: Thiram-induced changes in the expression of genes relating to vascularization and tibial dyschondroplasia. Poult Sci. 2007 Nov;86(11):2390-5.

It appears that some of the early effects of thiram on the growth plate may be the failure of genes encoding VEGF receptors and Bcl-2 resulting from endothelial cell death, which compromise vascularization, cartilage remodeling, and the removal of dead chondrocytes leading to TD lesions.
112(1,2,2,2) Details