| Name | neurotrophic factors |
|---|---|
| Synonyms | ARTN; Artemin; Artemin precursor; EVN; Enovin; NBN; Neublastin; Neuroblastin… |
| Name | diazinon |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17589599 | Slotkin TA, Seidler FJ, Fumagalli F: Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily. Environ Health Perspect. 2007 Jun;115(6):909-16. Epub 2007 Feb 27. |
33(0,1,1,3) | Details |
| 19130878 | Slotkin TA, Seidler FJ, Fumagalli F: Unrelated developmental neurotoxicants elicit similar transcriptional profiles for effects on neurotrophic factors and their receptors in an in vitro model. Neurotoxicol Teratol. 2010 Jan-Feb;32(1):42-51. Epub 2008 Dec 13. We examined an organophosphate pesticide (diazinon), an organochlorine pesticide (dieldrin) and a metal (Ni (2+)) for effects on the expression of neurotrophic factors and their receptors and modulators in differentiating PC12 cells, an in vitro model of neuronal development. |
32(0,1,1,2) | Details |
| 19368821 | Slotkin TA, Seidler FJ: Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent in PC12 cells. Brain Res. 2009 Mar 31;1263:23-32. Epub 2009 Feb 5. We compared two organophosphate insecticides (chlorpyrifos, diazinon) with an organochlorine (dieldrin) and a metal (Ni (2+)) for similarities and differences in their effects on gene expression encoding subtypes of protein kinase C and their modulators, a cell signaling cascade that integrates the actions of neurotrophic factors involved in brain development. |
6(0,0,1,1) | Details |
| 18502319 | Slotkin TA, Seidler FJ, Fumagalli F: Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro. Brain Res Bull. 2008 Jul 1;76(4):424-38. Epub 2008 Feb 1. We administered chlorpyrifos and diazinon to neonatal rats on postnatal days 1-4 at doses devoid of systemic toxicity or growth impairment, and spanning the threshold for barely-detectable cholinesterase inhibition. |
5(0,0,0,5) | Details |