Protein Information

Name cytochrome P450 (protein family or complex)
Synonyms cytochrome P450; cytochrome P 450; CYP450; CYP 450

Compound Information

Name penconazole
CAS

Reference List

PubMed Abstract RScore(About this table)
3097533 Niggli B, Friederich U, Hann D, Wurgler FE: Endogenous promutagen activation in the yeast Saccharomyces cerevisiae: factors influencing aflatoxin B1 mutagenicity. Mutat Res. 1986 Dec;175(4):223-9.

The fact that different cytochrome P-450 inhibitors (ellipticine, penconazole and propiconazole as yeast-specific P-450 inhibitors) abolished the AFB1-induced mutagenicity indicates that activation of the promutagen AFB1 depends on the cytochrome P-450-catalyzed electron-transfer reactions.
82(1,1,1,2) Details
9151426 Nega E, Grunwaldt G: Evidence for and characterization of cytochrome P-450 in Neurospora crassa. J Basic Microbiol. 1997;37(2):139-45.

4(0,0,0,4) Details
7481747 Johnston G: The study of interactive effects of pollutants: a biomarker approach. Sci Total Environ. 1995 Oct 27;171(1-3):205-12.

Birds pretreated with the EBI penconazole showed significantly greater inhibition of serum BuChE activity at 1, 4 and 24 h after malathion administration than did controls.
The mechanism of increased activation of malathion due to induction of cytochrome P-450 by prochloraz is reviewed.
1(0,0,0,1) Details