| Name | demethylase |
|---|---|
| Synonyms | DMTase; Demethylase; MBD 2; MBD2; Methyl CpG binding domain protein 2; Methyl CpG binding protein MBD2; NY CO 41; Demethylases… |
| Name | triadimenol |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18257249 | Xiao M, Yang JY, Xiao WJ, Yang S: [Application of binding spectra in DMIs fungicide screening] . Sheng Wu Gong Cheng Xue Bao. 2007 Nov;23(6):1129-34. In order to establish a fast and accurate method for novel DMIs fungicide screening, 14alpha-demethylase of Magnaporthe grisea expressed in E. coli was used as target enzyme and the DMI fungicides diniconazole, tebuconazole, triadimenol and triadimefon were used as representative fungicides, the effects of enzyme activity, enzyme purity and concentration on the binding spectra were investigated. |
32(0,1,1,2) | Details |
| 2205265 | Yoshida Y, Aoyama Y: Stereoselective interaction of an azole antifungal agent with its target, lanosterol 14 alpha-demethylase (cytochrome P-45014DM): a model study with stereoisomers of triadimenol and purified cytochrome P-45014DM from yeast. Chirality. 1990;2(1):10-5. The effect of the four triadimenol stereoisomers on the purified yeast lanosterol 14 alpha-demethylase (cytochrome P-45014DM), the primary target of azole antifungal agents, was studied. (1S,2R)-Triadimenol was the most potent demethylase inhibitor and bound quantitatively to the enzyme below 0.05 microM. |
32(0,1,1,2) | Details |
| 15916909 | Wyand RA, Brown JK: Sequence variation in the CYP51 gene of Blumeria graminis associated with resistance to sterol demethylase inhibiting fungicides. Fungal Genet Biol. 2005 Aug;42(8):726-35. However, genetic analysis of resistance to the DMI triadimenol indicates that mutation of the CYP51 gene is not the only mechanism of resistance operating in B. graminis. |
2(0,0,0,2) | Details |
| 9251183 | Delye C, Laigret F, Corio-Costet MF: A mutation in the 14 alpha-demethylase gene of Uncinula necator that correlates with resistance to a sterol biosynthesis inhibitor. Appl Environ Microbiol. 1997 Aug;63(8):2966-70. The sensitivity of 91 single-spore field isolates of U. necator to triadimenol was assessed by using a leaf disc assay. |
2(0,0,0,2) | Details |