| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | captan |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 121071 | Dalvi RR, Ashley WM: Protective effect of on the in vitro inhibition of hepatic cytochrome P-450 by captan. Drug Chem Toxicol. 1979;2(3):245-55. |
119(1,2,3,4) | Details |
| 663942 | Peeples A, Dalvi RR: Toxicologic studies of N-trichloromethylthio-4-cyclohexene-1,2-dicarboximide (captan): its metabolism by rat liver drug-metabolizing enzyme system. Toxicology. 1978 Apr;9(4):341-51. In vitro incubations of rat liver microsomes with captan resulted in a profound loss of cytochrome P-450 and the acitivty of benzphetamine N-demethylase as well as hydroxylase. |
7(0,0,1,2) | Details |
| 3385136 | Dalvi RR: Involvement of in the reduction of captan-induced in vivo inhibition of monooxygenases and liver toxicity in the rat. J Environ Sci Health B. 1988 Apr;23(2):171-8. The single dose of captan caused marked depression of microsomal cytochrome P-450 and the activity of benzphetamine N-demethylase and hydroxylase, and moderate elevation of the serum enzymes indicative of liver damage. |
6(0,0,1,1) | Details |
| 15388237 | Suzuki T, Nojiri H, Isono H, Ochi T: Oxidative damages in isolated rat hepatocytes treated with the organochlorine fungicides captan, dichlofluanid and chlorothalonil. Toxicology. 2004 Nov 15;204(2-3):97-107. The antioxidant and cytochrome P450 inhibitor SKF-525A effectively prevented cytotoxicity and lipid peroxidation. |
2(0,0,0,2) | Details |
| 8820859 | Potter S, Moreland DE, Kreuz K, Ward E: Induction of cytochrome P450 genes by in maize. Drug Metabol Drug Interact. 1995;12(3-4):317-27. |
2(0,0,0,2) | Details |
| 11673071 | Rahden-Staron I, Czeczot H, Szumilo M: Induction of rat liver cytochrome P450 isoenzymes CYP 1A and CYP 2B by different fungicides, nitrofurans, and Mutat Res. 2001 Nov 15;498(1-2):57-66. We studied induction of the CYP 1A or CYP 2B monooxygenases in rat liver by the fungicides: thiram, captan, captafol, dodine and the drugs: nitrofurazone, furazolidone and the plant |
2(0,0,0,2) | Details |