| Name | c jun |
|---|---|
| Synonyms | AP1; Activator protein 1; JUN; Proto oncogene c jun; Protooncogene c jun; Transcription factor AP 1; V jun avian sarcoma virus 17 oncogene homolog; c Jun… |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10696784 | Matsuoka M, Wispriyono B, Iryo Y, Igisu H: Mercury activates c-Jun N-terminal kinase and induces c-jun expression in LLC-PK1 cells. Toxicol Sci. 2000 Feb;53(2):361-8. |
5(0,0,0,5) | Details |
| 9779822 | Akhand AA, Kato M, Suzuki H, Miyata T, Nakashima I: Level of HgCl2-mediated phosphorylation of intracellular proteins determines death of thymic T-lymphocytes with or without DNA fragmentation. J Cell Biochem. 1998 Nov 1;71(2):243-53. The c-Jun amino terminal kinase (p54), which is a distant relative of the MAPK family, was also phosphorylated by the treatment with Hg2+. |
3(0,0,0,3) | Details |
| 10544060 | Turney KD, Parrish AR, Orozco J, Gandolfi AJ: Selective activation in the MAPK pathway by Hg (II) in precision-cut rabbit renal cortical slices. Toxicol Appl Pharmacol. 1999 Nov 1;160(3):262-70. Cortical slices (275 microm) were obtained from 1.0 kg NZW rabbits and exposed to mercuric chloride [Hg (II)] at concentrations of 0.01-10 microM for 2-8 h. A dose-dependent induction of the DNA binding activity of the AP-1 transcription factor after 4 h of Hg (II) exposure correlated with a dose-dependent enhancement of c-jun gene expression following 2 h of Hg (II) exposure. |
3(0,0,0,3) | Details |
| 15302099 | Matsuoka M, Igisu H, Nakagawa K, Katada T, Nishina H: Requirement of MKK4 and MKK7 for CdCl2- or HgCl2-induced activation of c-Jun NH2-terminal kinase in mouse embryonic stem cells. Toxicol Lett. 2004 Sep 10;152(2):175-81. |
2(0,0,0,2) | Details |
| 10861847 | Du J, Suzuki H, Nagase F, Akhand AA, Yokoyama T, Nakashima I: Mercuric chloride stimulates distinct signal transduction pathway for DNA synthesis in a T-cell line, CTLL-2. J Cell Biochem. 2000 Jun 6;78(3):500-8. Stimulation of CTLL-2 cells with IL-2 induced phosphorylation on extracellular signal-regulated kinases more intensively than on c-Jun NH2-terminal kinases (JNKs), and provoked phosphorylation of Janus kinases (JAKs) and signal transducers and activators of transcription (STATs). |
1(0,0,0,1) | Details |