Protein Information

Name connective tissue growth factor
Synonyms CCN 2; CCN2; CTGF; Connective tissue growth factor; Connective tissue growth factor precursor; FISP 12 protein; HCS24; Hypertrophic chondrocyte specific protein 24…

Compound Information

Name biphenyl
CAS 1,1′-biphenyl

Reference List

PubMed Abstract RScore(About this table)
19065061 Ren X, Guan G, Liu G, Liu G: Irbesartan ameliorates diabetic nephropathy by reducing the expression of connective tissue growth factor and alpha-smooth-muscle actin in the tubulointerstitium of diabetic rats. Pharmacology. 2009;83(2):80-7. Epub 2008 Dec 9.

6(0,0,0,6) Details
18162196 Fliegner D, Westermann D, Riad A, Schubert C, Becher E, Fielitz J, Tschope C, Regitz-Zagrosek V: Up-regulation of PPARgamma in myocardial infarction. Eur J Heart Fail. 2008 Jan;10(1):30-8. Epub 2007 Dec 27.


In parallel, expression of CTGF was increased 10-fold in the infarcted zone.
2(0,0,0,2) Details
18045851 Tu X, Chen X, Xie Y, Shi S, Wang J, Chen Y, Li J: Anti-inflammatory renoprotective effect of clopidogrel and irbesartan in chronic renal injury. J Am Soc Nephrol. 2008 Jan;19(1):77-83. Epub 2007 Nov 28.


Combination therapy almost completely abolished macrophage infiltration and attenuated the expression of monocyte chemoattractant protein-1, intercellular adhesion molecule-1, TGF-beta (1), and connective tissue growth factor.
1(0,0,0,1) Details