| Name | superoxide dismutase |
|---|---|
| Synonyms | IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD… |
| Name | biphenyl |
|---|---|
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19459740 | Kaiser P, Youssouf MS, Tasduq SA, Singh S, Sharma SC, Singh GD, Gupta VK, Gupta BD, Johri RK: Anti-allergic effects of herbal product from Allium cepa (bulb). J Med Food. 2009 Apr;12(2):374-82. In this experiment ALC-02 also caused a substantial reduction in lipid peroxidation in BALF/lung tissue and augmented superoxide dismutase activity in lung tissue. |
1(0,0,0,1) | Details |
| 18273903 | Sinha M, Manna P, Sil PC: Protective effect of arjunolic acid against arsenic-induced oxidative stress in mouse brain. J Biochem Mol Toxicol. 2008 Feb;22(1):15-26. Oral administration of arsenite at a dose of 10 mg/kg body weight for 2 days significantly decreased the activities of antioxidant enzymes, superoxide dismutase, catalase, glutathione-S-transferase, glutathione reductase and peroxidase, the level of cellular metabolites, total thiols and increased the level of |
1(0,0,0,1) | Details |
| 18956176 | Yu YN, Chen H, Li Y: Protect effect of bicyclol on cisplatin-induced nephrotoxicity in mice. Arch Toxicol. 2009 Apr;83(4):381-7. Epub 2008 Oct 28. The formation of kidney malondialdehyde with a concomitant reduction of were also inhibited by bicyclol, while the activities of kidney superoxide dismutase, catalase and peroxidase were all increased, respectively. |
1(0,0,0,1) | Details |
| 19210495 | Yu YN, Chen H, Li Y: Effect of bicyclol on cisplatin-induced hepatotoxicity in the hepatocarcinoma 22 tumour-bearing mice. Basic Clin Pharmacol Toxicol. 2009 Apr;104(4):300-5. Epub 2009 Feb 2. The formation of liver malondialdehyde with a concomitant reduction of was also inhibited by bicyclol, while the activities of liver superoxide dismutase, catalase and peroxidase were all increased, respectively. |
1(0,0,0,1) | Details |
| 19282644 | Fukai S, Tanimoto S, Maeda A, Fukuda H, Okada Y, Nomura M: Pharmacological activity of compounds extracted from persimmon peel (Diospyros kaki THUNB.). J Oleo Sci. 2009;58(4):213-9. The 2-methoxy- (8) which is component of persimmon peel had high antioxidant activity on the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay and SOD (superoxide dismutase) assay. |
1(0,0,0,1) | Details |
| 18538762 | Lu C, Su LY, Lee RM, Gao YJ: mediates angiotensin II-induced potentiation of contractile response to sympathetic stimulation. Eur J Pharmacol. 2008 Jul 28;589(1-3):188-93. Epub 2008 May 5. This potentiation was blunted by an angiotensin AT (1) receptor antagonist (2-ethoxy-1-[[2'-(1H-tetrazol-5-yl) biphenyl-4-yl] methyl]-1H-benzimidazole- 7-carboxylic acid, CV-11974), NAD (P) H oxidase inhibitor (apocynin), superoxide dismutase (SOD) and its mimetic tiron, but not affected by angiotensin AT (2) receptor antagonist and inhibitors of xanthine oxidase, cytochrome P450, and cyclooxygenase. |
0(0,0,0,0) | Details |
| 18577607 | Wang L, Piao XL, Kim SW, Piao XS, Shen YB, Lee HS: Effects of Forsythia suspensa extract on growth performance, nutrient digestibility, and antioxidant activities in broiler chickens under high ambient temperature. Poult Sci. 2008 Jul;87(7):1287-94. Furthermore, birds in FS had greater (P < 0.05) total antioxidant capacity and superoxide dismutase activity and lower (P < 0.05) malondialdehyde activity in the serum than birds in NC. |
3(0,0,0,3) | Details |
| 18930849 | Temraz A, El-Tantawy WH: Characterization of antioxidant activity of extract from Artemisia vulgaris. Pak J Pharm Sci. 2008 Oct;21(4):321-6. Determination of serum level, blood level and superoxide dismutase activity in rats treated with 100 mg/Kg of Artemisia vulgaris extract. |
2(0,0,0,2) | Details |
| 19328559 | Franck T, Kohnen S, de la Rebiere G, Deby-Dupont G, Deby C, Niesten A, Serteyn D: Activation of equine neutrophils by phorbol or N-formyl-methionyl-leucyl- induces a different response in reactive species production and release of active myeloperoxidase. Vet Immunol Immunopathol. 2009 Aug 15;130(3-4):243-50. Epub 2009 Mar 4. When PMNs were pre-incubated with superoxide dismutase (SOD) prior to PMA activation, the lucigenin enhanced CL, which is linked to the (O2-) production, was much more decreased than KMB oxidation, linked to the -like radical production. |
1(0,0,0,1) | Details |
| 18502095 | Murugesan P, Muthusamy T, Balasubramanian K, Arunakaran J: Polychlorinated biphenyl (Aroclor 1254) inhibits biosynthesis and antioxidant enzymes in cultured rat Leydig cells. Reprod Toxicol. 2008 Aug;25(4):447-54. Epub 2008 Apr 18. In addition, Leydig cellular enzymatic antioxidants such as superoxide dismutase (SOD), catalase (CAT), peroxidase (GPx), glutathione reductase (GR), gamma-glutamyl transpeptidase (gamma-GT), glutathione-S-transferase (GST) and non-enzymatic antioxidants such as and E were assayed. |
1(0,0,0,1) | Details |
| 19796678 | Zhu Y, Kalen AL, Li L, Lehmler HJ, Robertson LW, Goswami PC, Spitz DR, Aykin-Burns N: Polychlorinated-biphenyl-induced oxidative stress and cytotoxicity can be mitigated by antioxidants after exposure. Free Radic Biol Med. 2009 Dec 15;47(12):1762-71. Epub 2009 Sep 28. These results support the hypothesis that exposure of exponentially growing human breast and prostate epithelial cells to PCBs causes increased steady-state levels of intracellular O (2)(*-) and H (2) O (2), induction of MnSOD or CuZnSOD activity, and clonogenic cell killing that could be inhibited by a clinically relevant thiol antioxidant, NAC, as well as by catalase and superoxide dismutase after PCB exposure. |
1(0,0,0,1) | Details |
| 20307652 | Chaudhuri L, Sarsour EH, Kalen AL, Aykin-Burns N, Spitz DR, Goswami PC: Polychlorinated biphenyl induced ROS signaling delays the entry of quiescent human breast epithelial cells into the proliferative cycle. Free Radic Biol Med. 2010 Mar 19. Pretreatment of quiescent cells with polyethylene glycol-conjugated superoxide dismutase and catalase suppressed 4-Cl-BQ induced increase in ROS levels, which was consistent with an increase in cyclin D1 accumulation, and entry into S phase. |
1(0,0,0,1) | Details |
| 18640730 | Gunawickrama SH, Aarsaether N, Orbea A, Cajaraville MP, Goksoyr A: PCB77 (3,3',4,4'-tetrachlorobiphenyl) co-exposure prolongs CYP1A induction, and sustains oxidative stress in B (a) P-exposed turbot, Scophthalmus maximus, in a long-term study. Aquat Toxicol. 2008 Aug 29;89(2):65-74. Epub 2008 Jun 8. The results indicate synergistic effects of polycyclic aromatic hydrocarbon (PAH) and polychlorinated biphenyl (PCB) exposure in the aquatic environment. Both exposed groups demonstrated evidence for lasting oxidative stress as hepatic superoxide dismutase, catalase and peroxidase activities were significantly altered (p <0.05) with symptomatic pro-oxidant associations among them. |
1(0,0,0,1) | Details |
| 19429327 | Shen X, Tang Y, Yang R, Yu L, Fang T, Duan JA: The protective effect of Zizyphus jujube fruit on carbon tetrachloride-induced hepatic injury in mice by anti-oxidative activities. J Ethnopharmacol. 2009 Apr 21;122(3):555-60. Epub 2009 Feb 7. Product of lipid peroxidation (MDA), activities of superoxide dismutase (SOD), catalase (CAT), and peroxidase (GSH-Px), and (GSH) contents were evaluated for oxidative stress in hepatic injury. |
1(0,0,0,1) | Details |
| 19147108 | Hu H, Zhang Z, Lei Z, Yang Y, Sugiura N: Comparative study of antioxidant activity and antiproliferative effect of hot water and extracts from the mushroom Inonotus obliquus. J Biosci Bioeng. 2009 Jan;107(1):42-8. Hot water (50 degrees C, 70 degrees C, and 80 degrees C) and crude extracts of I. obliquus were investigated for their antioxidant activity with superoxide dismutase (SOD) and (1,1-diphenyl-2-picryhydrazyl) (DPPH) radical-scavenging activity assays. |
1(0,0,0,1) | Details |
| 17967502 | Saito J, Shibuya K, Nagase H: Anti-clastogenic effect of magnolol on benzo (a) pyrene-induced clastogenicity in mice. Food Chem Toxicol. 2008 Feb;46(2):694-700. Epub 2007 Sep 26. In order to elucidate the mechanism behind this effect, we measured the activity of the detoxifying enzymes [UDP-glucuronosyltransferase (UGT) and glutathione-S-transferase (GST)] and antioxidative enzymes [superoxide dismutase (SOD) and catalase] in the liver when treated with an oral administration of magnolol at various administration times. |
1(0,0,0,1) | Details |
| 18361750 | Spada PD, de Souza GG, Bortolini GV, Henriques JA, Salvador M: Antioxidant, mutagenic, and antimutagenic activity of frozen fruits. J Med Food. 2008 Mar;11(1):144-51. Antioxidant assays included 2,2-diphenyl-1-picrylhydrazyl radical (DPPH (.)) scavenging activity and determination of superoxide dismutase (SOD)- and catalase (CAT)-like activities. |
1(0,0,0,1) | Details |
| 19427356 | Sun LN, Shen J, Su F, Wang Q, Zhu YJ, Lou XE, Liang HW, Bruce IC, Xia Q: Bicyclol attenuates oxidative stress and neuronal damage following transient forebrain ischemia in mouse cortex and hippocampus. Neurosci Lett. 2009 Aug 7;459(2):84-7. Epub 2009 May 7. After different times of reperfusion, the histopathological changes and the levels of mitochondria-generated reactive species (ROS), malondialdehyde (MDA) and the activity of superoxide dismutase (SOD) in the cortex and hippocampus were measured. |
1(0,0,0,1) | Details |
| 18022343 | Lee SJ, Lim KT: Glycoprotein of Zanthoxylum piperitum DC has a hepatoprotective effect via anti-oxidative character in vivo and in vitro. Toxicol In Vitro. 2008 Mar;22(2):376-85. Epub 2007 Oct 14. In addition, administration of ZPDC glycoprotein (20mg/kg) lowers the levels of lactate dehydrogenase, transaminase, and thiobarbituric acid reactive substances, whereas increases that of accompanying the normalizing effects on the activity of hepatic anti-oxidant enzymes (superoxide dismutase, catalase, and peroxidase) in mouse model of carbon tetrachloride-stimulated acute liver injury. |
1(0,0,0,1) | Details |
| 18371952 | Zhao J, Chen H, Li Y: Protective effect of bicyclol on acute -induced liver injury in mice. Eur J Pharmacol. 2008 May 31;586(1-3):322-31. Epub 2008 Feb 29. In addition, bicyclol remarkably alleviated the formation of thiobarbituric acid-reactive substance and restored impaired antioxidants, including superoxide dismutase, catalase, peroxidase, and glutathione reductase. |
1(0,0,0,1) | Details |
| 18306454 | Lee SH, Heo SI, Li L, Lee MJ, Wang MH: Antioxidant and hepatoprotective activities of Cirsium setidens Nakai against CCl4-induced liver damage. Am J Chin Med. 2008;36(1):107-14. The n-BuOH fraction reduced CCl (4)-induced liver injury in rats, and transcript levels of genes encoding antioxidant enzymes such as glutathione peroxidase 1 (GPO1), glutathione peroxidase 3 (GPO3) and superoxide dismutase (SOD1) were elevated in the livers of rats treated with this fraction (500 mg/kg). |
1(0,0,0,1) | Details |
| 18601970 | Vardi N, Parlakpinar H, Ozturk F, Ates B, Gul M, Cetin A, Erdogan A, Otlu A: Potent protective effect of apricot and on methotrexate-induced intestinal oxidative damage in rats. Food Chem Toxicol. 2008 Sep;46(9):3015-22. Epub 2008 Jun 14. Parallel to histological results, malondialdehyde (MDA) content and myeloperoxidase (MPO) activity were found to be increased, whereas superoxide dismutase (SOD), catalase (CAT), peroxidase (GP-x) activities and (GSH) content were decreased in the MTX group. |
1(0,0,0,1) | Details |
| 18998401 | Yang WM, Liu JK, Hu L, Dong ZJ, Wu WL, Chen ZH: Antioxidant properties of natural p-terphenyl derivatives from the mushroom Thelephora ganbajun. Z Naturforsch C. 2004 May-Jun;59(5-6):359-62. Compounds 1-3 increased superoxide dismutase (SOD) activity with EC50 values of 182, 74, 204 microM. |
1(0,0,0,1) | Details |
| 19109869 | Yang TC, Zhang SW, Sun LN, Wang H, Ren AM: Magnolol attenuates sepsis-induced gastrointestinal dysmotility in rats by modulating inflammatory mediators. World J Gastroenterol. 2008 Dec 28;14(48):7353-60. In addition, antioxidant activity was determined by measuring malondialdehyde (MDA) concentration and superoxide dismutase (SOD) activity in the intestine 2 h after LPS injection. |
1(0,0,0,1) | Details |
| 17910617 | Manna P, Sinha M, Sil PC: Protection of arsenic-induced hepatic disorder by arjunolic acid. Basic Clin Pharmacol Toxicol. 2007 Nov;101(5):333-8. Administration of arsenite at a dose of 10 mg/kg body weight for 2 days significantly reduced the activities of antioxidant enzymes, superoxide dismutase, catalase, glutathione S-transferase, glutathione reductase and peroxidase as well as depleted the level of and total thiols. |
1(0,0,0,1) | Details |
| 19309147 | Ajisaka K, Agawa S, Nagumo S, Kurato K, Yokoyama T, Arai K, Miyazaki T: Evaluation and comparison of the antioxidative potency of various carbohydrates using different methods. J Agric Food Chem. 2009 Apr 22;57(8):3102-7. A detailed analysis of the antioxidative activity of 12 carbohydrates including fucoidan, agaro-oligosaccharide, 2-deoxy-scyllo-inosose (DOI), Galbeta1-4DOI, D-mannosamine, D-galactosamine, and colominic acid was performed using four established methods: 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, ferric reducing antioxidant power (FRAP) assay, superoxide dismutase (SOD) activity assay, and the method. |
1(0,0,0,1) | Details |
| 18538307 | Duong TT, Antao S, Ellis NA, Myers SJ, Witting PK: Supplementation with a synthetic polyphenol limits oxidative stress and enhances neuronal cell viability in response to hypoxia-re-oxygenation injury. Brain Res. 2008 Jul 11;1219:8-18. Epub 2008 Apr 27. Expression of genes encoding for hypoxia-inducible factor 1-alpha (HIF1-alpha), inducible haemoxygenase-1 (HO-1), glucose transporter-1 (Glut-1), the -sensor neuroglobin (Nb) and Cu,Zn-superoxide dismutase (SOD1), catalase (CAT) and glutathione peroxidase-1 (Gpx-1) increased significantly in response to the insult. In contrast, ROS accumulation, the endogenous gene response and cell death was limited in neuronal cells pre-incubated with 50 or 100, but not 10 microM of the phenolic antioxidant 3,3',5,5'-tetra-t-butyl-biphenyl-4,4'-diol (BP) prior to H/R injury. |
1(0,0,0,1) | Details |
| 20074268 | Atessahin A, Turk G, Yilmaz S, Sonmez M, Sakin F, Ceribasi AO: Modulatory Effects of and on Reproductive Dysfunction Induced by Polychlorinated Biphenyl (Aroclor 1254) in Male Rats. Basic Clin Pharmacol Toxicol. 2010 Jan 14. AR administration caused statistically significant decreases in body-weight, epididymal sperm concentration, testicular superoxide dismutase activity, diameters of seminiferous tubules, germinal cell layer thickness and Johnsen's testicular score, and increases in relative weights of testis, epidydimis and seminal vesicles, rates of abnormal sperm and apoptotic cell expression along with degeneration, desquamation and disorganization in spermatogenic cells, and interstitial oedema and congestion in testicular tissue. |
1(0,0,0,1) | Details |
| 18687761 | Zhang M, Zhou SH, Zhao SP, Liu QM, Li XP, Shen XQ: Irbesartan attenuates Ang II-induced BMP-2 expression in human umbilical vein endothelial cells. Vasc Med. 2008 Aug;13(3):239-45. Furthermore, the increased levels of MDA (malondialdehyde) in conditioned media and the decrease in activities of total superoxide dismutases (SOD) caused by Ang II were reversed by irbesartan or PDTC treatment. |
1(0,0,0,1) | Details |
| 19268528 | de Lamirande E, Lamothe G, Villemure M: Control of and formation during human sperm capacitation. Free Radic Biol Med. 2009 May 15;46(10):1420-7. Epub 2009 Mar 4. chelators (TPEN and EDTA) and sulfhydryl-targeted compounds (diamide and N-ethylmaleimide) stimulated capacitation and formation of O (2).(-) and NO.; superoxide dismutase (SOD) and synthase inhibitor (L-NMMA) prevented these events. |
1(0,0,0,1) | Details |
| 19445998 | Kong CS, Kim JA, Qian ZJ, Kim YA, Lee JI, Kim SK, Nam TJ, Seo Y: Protective effect of 3-O-beta-D-glucopyranoside from Salicornia herbacea against oxidation-induced cell damage. Food Chem Toxicol. 2009 Aug;47(8):1914-20. Epub 2009 May 13. Further, antioxidative mechanisms by compound 1 were examined by measuring the intracellular (GSH) level and expression levels of antioxidant enzymes such as superoxide dismutase (SOD), catalase, glutathione reductase and heme oxygenase-1 (HO-1). |
1(0,0,0,1) | Details |