Protein Information

Name glutathione S transferase
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name chlorothalonil
CAS 2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile

Reference List

PubMed Abstract RScore(About this table)
15357291 Kim YM, Park K, Jung SH, Choi JH, Kim WC, Joo GJ, Rhee IK: Chlorothalonil-biotransformation by glutathione S-transferase of Escherichia coli. J Microbiol. 2004 Mar;42(1):42-6.
12(0,0,2,2) Details
2069587 Gallagher EP, Kedderis GL, Di Giulio RT: Glutathione S-transferase-mediated chlorothalonil metabolism in liver and gill subcellular fractions of channel catfish. Biochem Pharmacol. 1991 Jun 21;42(1):139-45.
2(0,0,0,2) Details
19694443 Xia XJ, Zhang Y, Wu JX, Wang JT, Zhou YH, Shi K, Yu YL, Yu JQ: Brassinosteroids promote metabolism of pesticides in cucumber. J Agric Food Chem. 2009 Sep 23;57(18):8406-13.

Importantly, the stimulatory effect of EBR on pesticide metabolism was also observed for cypermethrin, chlorothalonil, and carbendazim, which was attributed to the enhanced activity and genes involved in pesticide metabolism.
EBR had a positive effect on the activation of glutathione S-transferase (GST), peroxidase (POD), and glutathione reductase (GR) after treatment with chlorpyrifos, although the effect on GR was attenuated at later time points when plants were treated with 1 mM chlorpyrifos.
1(0,0,0,1) Details
15212468 Kim YM, Park K, Joo GJ, Jeong EM, Kim JE, Rhee IK: Glutathione-dependent biotransformation of the fungicide chlorothalonil. . J Agric Food Chem. 2004 Jun 30;52(13):4192-6.

The gene encoding glutathione S-transferase (GST) of O. anthropi SH35B was expressed in Escherichia coli, and the GST was subsequently purified by affinity chromatography.
1(0,0,0,1) Details
20148249 Liang B, Li R, Jiang D, Sun J, Qiu J, Zhao Y, Li S, Jiang J: Hydrolytic Dechlorination of Chlorothalonil by Ochrobactrum sp. Curr Microbiol. 2010 Feb 11.

A glutathione S-transferase (GST) coding gene, which showed 88% sequence similarity with that from Ochrobactrum anthropi SH35B, was cloned from strain CTN-11.
1(0,0,0,1) Details
20015538 White PM, Potter TL, Culbreath AK: Fungicide dissipation and impact on metolachlor aerobic soil degradation and soil microbial dynamics. Sci Total Environ. 2010 Feb 15;408(6):1393-402. Epub 2009 Dec 16.

This suggested that the fungicide impacted soil glutathione-S-transferase (GST) activity.
Our study objective was to determine the effects of 4 peanut fungicides, chlorothalonil (2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile), tebuconazole (alpha-[2-(4-chlorophenyl) ethyl]-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazo le-1-ethanol), flutriafol (alpha-(2-fluorophenyl)-alpha-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol ), and cyproconazole (alpha-(4-chlorophenyl)-alpha-(1-cyclopropylethyl)-1H-1,2,4-triazole-1-eth anol) on the dissipation kinetics of the herbicide, metolachlor (2-chloro-N-(6-ethyl-o-tolyl)-N-[(1RS)-2-methoxy-1-methylethyl] acetamide), and on the soil microbial community.
1(0,0,0,1) Details
20347472 Wang J, Jiang Y, Chen S, Xia X, Shi K, Zhou Y, Yu Y, Yu J: The different responses of glutathione-dependent detoxification pathway to fungicide chlorothalonil and carbendazim in tomato leaves. Chemosphere. 2010 Mar 26.

0(0,0,0,0) Details