| Name | myeloperoxidase |
|---|---|
| Synonyms | 38 kDa MYELOPEROXIDASE; MPO; Myeloperoxidase; Myeloperoxidase precursor; Peroxidase (Myeloperoxidase); Myeloperoxidases; Myeloperoxidase precursors; Peroxidase (Myeloperoxidase)s |
| Name | pentachlorophenol |
|---|---|
| CAS | 2,3,4,5,6-pentachlorophenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15833038 | Dai J, Sloat AL, Wright MW, Manderville RA: Role of phenoxyl radicals in DNA adduction by chlorophenol xenobiotics following peroxidase activation. Chem Res Toxicol. 2005 Apr;18(4):771-9. Recently, we characterized the ability of pentachlorophenol (PCP) to react covalently with (dG) following treatment with horseradish peroxidase (HRP)/H2O2 or myeloperoxidase to yield a C8-dG (O)-adduct that suggested the intermediacy of the pentachlorophenoxyl radical in covalent bond formation [Dai, J., Wright, M. |
81(1,1,1,1) | Details |
| 10739033 | Wittsiepe J, Kullmann Y, Schrey P, Selenka F, Wilhelm M: Myeloperoxidase-catalyzed formation of PCDD/F from chlorophenols. Chemosphere. 2000 May-Jun;40(9-11):963-8. This is shown for 2,4,5-tri-, 2,3,4,6-tetra-and pentachlorophenol with myeloperoxidase recovered from human leucocytes in the presence of peroxide. |
7(0,0,1,2) | Details |
| 10403663 | Wittsiepe J, Kullmann Y, Schrey P, Selenka F, Wilhelm M: Peroxidase-catalyzed in vitro formation of polychlorinated dibenzo-p-dioxins and dibenzofurans from chlorophenols. Toxicol Lett. 1999 Jun 1;106(2-3):191-200. This is shown for 2,4,5-tri-, 2,3,4,6-tetra- and pentachlorophenol with plant horseradish peroxidase and with myeloperoxidase recovered from human leukocytes, each in the presence of peroxide. |
6(0,0,1,1) | Details |
| 12870883 | Dai J, Wright MW, Manderville RA: An -bonded c8- nucleoside adduct of pentachlorophenol by peroxidase activation: evidence for ambident c8 reactivity by phenoxyl radicals. Chem Res Toxicol. 2003 Jul;16(7):817-21. Treatment of PCP (100 microM) with horseradish peroxidase (HRP/H (2) O (2)) or myeloperoxidase (MPx/H (2) O (2), from human leukocytes) in the presence of excess (dG, 2 mM) led to the isolation and identification of the -bonded C8-dG nucleoside adduct 4. |
1(0,0,0,1) | Details |