Protein Information

Name HNF4
Synonyms HNF 4; HNF 4 alpha; HNF4; HNF4 alpha; HNF4A; HNF4a7; HNF4a8; HNF4a9…

Compound Information

Name pentachlorophenol
CAS 2,3,4,5,6-pentachlorophenol

Reference List

PubMed Abstract RScore(About this table)
19463090 Kaledin VI, Pakharukova MY, Pivovarova EN, Kropachev KY, Baginskaya NV, Vasilieva ED, Ilnitskaya SI, Nikitenko EV, Kobzev VF, Merkulova TI: Correlation between hepatocarcinogenic effect of estragole and its influence on glucocorticoid induction of liver-specific enzymes and activities of FOXA and HNF4 transcription factors in mouse and rat liver. Biochemistry. 2009 Apr;74(4):377-84.

Pentachlorophenol, preventing hepatocarcinogenic effect of estragole, abolishes inhibitory influence of the latter on the TAT and TO glucocorticoid induction and restores DNA-binding activity of FOXA and HNF4.
83(1,1,1,3) Details