Protein Information

Name androgen receptor
Synonyms AIS; AR; Androgen receptor; DHTR; Dihydrotestosterone receptor; HUMARA; KD; NR3C4…

Compound Information

Name carbendazim
CAS

Reference List

PubMed Abstract RScore(About this table)
15371226 Lu SY, Liao JW, Kuo ML, Wang SC, Hwang JS, Ueng TH: Endocrine-disrupting activity in carbendazim-induced reproductive and developmental toxicity in rats. J Toxicol Environ Health A. 2004 Oct 8;67(19):1501-15.

Additions of 5, 50, and 500 microM carbendazim to testis extract from untreated rats replaced binding of [3H]-5 alpha-dihydrotestosterone to androgen receptor in a concentration-dependent manner.
155(1,3,5,5) Details
15885261 Yamada T, Sumida K, Saito K, Ueda S, Yabushita S, Sukata T, Kawamura S, Okuno Y, Seki T: Functional genomics may allow accurate categorization of the benzimidazole fungicide benomyl: lack of ability to act via steroid-receptor-mediated mechanisms. Toxicol Appl Pharmacol. 2005 May 15;205(1):11-30.


Although benomyl and its metabolite carbendazim have been shown to adversely affect male reproduction, the mechanisms of action do not appear to involve the endocrine system.
0(0,0,0,0) Details