Protein Information

Name glutathione S transferase
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name pirimiphos-methyl
CAS

Reference List

PubMed Abstract RScore(About this table)
11758396 Yin D, Jin H, Yu H, Chen L: [A comparative study on the sensitivity and specificity of cholinesterase and glutathione s-transferase in Gammarus pulex L.]. Ying Yong Sheng Tai Xue Bao. 2001 Aug;12(4):615-8.

Studies on the influences of lindane, pirimiphos methyl, permethrin, zinc and dodecyl linear alkybenzene sulfonate (LAS) on the activity and toxicity of cholinesterase (ChE) and glutathione s-transferase (GST) in Gammarus pulex L. showed that only pirimiphos methyl caused a change in ChE activity in Gammarus, with a significant reduction in enzyme activity after 24 h and 48 h exposure.
32(0,1,1,2) Details
18240518 Rodriguez MM, Bisset JA, Fernandez D: Levels of insecticide resistance and resistance mechanisms in Aedes aegypti from some Latin American countries. J Am Mosq Control Assoc. 2007 Dec;23(4):420-9.

Biochemical tests showed high frequencies of esterase and glutathione-S-transferase activity; however, the frequency of altered acetylcholinesterase mechanism was low.
Eight Latin American strains of Aedes aegypti were evaluated for resistance to 6 organophosphates (temephos, malathion, fenthion, pirimiphos-methyl, fenitrothion, and chlorpirifos) and 4 pyrethroids (deltamethrin, lambdacyhalothrin, betacypermethrin, and cyfluthrin) under laboratory conditions.
1(0,0,0,1) Details
17710279 Dzul FA, Patricia Penilla R, Rodriguez AD: [Susceptibility and insecticide resistance mechanisms in Anopheles albimanus from the southern Yucatan Peninsula, Mexico]. Salud Publica Mex. 2007 Jul-Aug;49(4):302-11.

Blanco municipality in Quintana Roo and the Calakmul municipality in Campeche, were exposed to deltamethrin, DDT, pirimiphos-methyl and bendiocarb in susceptibility tests, as well as to biochemical assays in order to calculate the enzyme levels related to insecticide resistance.
Biochemical assays showed high levels of glutathione S-transferase (GST), cytochrome P450 and esterases (with pNPA substrate) in all villages.
1(0,0,0,1) Details
12061829 Callaghan A, Fisher TC, Grosso A, Holloway GJ, Crane M: Effect of temperature and pirimiphos methyl on biochemical biomarkers in Chironomus riparius Meigen. Ecotoxicol Environ Saf. 2002 Jun;52(2):128-33.

Two biochemical biomarkers, acetylcholinesterase (AChE) and glutathione S-transferase (GST), were measured in individual larvae from each treatment.
1(0,0,0,1) Details
12485579 Crane M, Sildanchandra W, Kheir R, Callaghan A: Relationship between biomarker activity and developmental endpoints in Chironomus riparius Meigen exposed to an organophosphate insecticide. Ecotoxicol Environ Saf. 2002 Nov;53(3):361-9.

The biomarkers acetylcholinesterase (AChE) and glutathione S-transferase (GST) were measured in fourth-instar Chironomus riparius Meigen larvae exposed to the organophosphate insecticide pirimiphos methyl (0, 5, 10, and 50ng/g) for 48 or 96h, and at high or low food ration.
6(0,0,1,1) Details
1463899 Hemingway J, Small GJ, Monro A, Sawyer BV, Kasap H: Insecticide resistance gene frequencies in Anopheles sacharovi populations of the Cukurova plain, Adana Province, Turkey. Med Vet Entomol. 1992 Oct;6(4):342-8.

The cross-resistance spectrum from this mechanism conferred resistance to malathion but not to the organophosphorus insecticide pirimiphos-methyl.
In addition to the acetylcholinesterase resistance mechanism there is evidence of an increased level of glutathione S-transferase in some of the An.sacharovi populations tested.
2(0,0,0,2) Details
11826536 Bisset JA, Rodriguez MM, Molina D, Diaz C, Soca LA: [High esterases as mechanism of resistance to organophosphate insecticides in Aedes aegypti strains]. Rev Cubana Med Trop. 2001 Jan-Apr;53(1):37-43.

Five strains of Aedes aegypti L. one from Cuba and 4 from Venezuela were evaluated to determine their resistance to organophosphate insecticides (temephos, chlorpiriphos and pirimiphos methyl).
The results of the biochemical tests proved the presence of esterase and glutathione-s-transferase at high frequency in almost every strain.
1(0,0,0,1) Details